Is There Clinical Significance to Coagulase-Negative Staphylococci Isolated from Blood Cultures?

Abstract

ÖZET Giriş: Bu çalışmada, kan kültürlerinden izole edilmiş koagülaz-negatif stafiloklar (KNS)'ın sıklığı ve gerçek kan dolaşımı infeksiyonlarının özelliklerinin incelenmesi amaçlanmıştır. Materyal ve

Evaluation of candidemia risk factors andCandidaspecies distribution in intensive care units among patients with and without COVID-19

“…While bacterial or viral coinfections are rarely observed during the diagnosis of COVID-19, an increase in the duration of hospital stay and the need for ICU admission, along with invasive procedures, leads to an elevated incidence of secondary infections. 22 , 23 …”

“…The isolated agents identified as Aeromonas hydrophila/caviae (n=2), Burkholderia cepacia (n=2), P. aeruginosa (n=2), Acinetobacter baumannii (n=2), S. aureus (n=2), C. albicans (n=2), C. glabrata (n=2), and C. kefyr (n=2). 23 Prior to COVID-19, 163 (11.9%) out of 1374 blood culture samples showed growth, with 35.0% being Gram-negative, 60.7% Gram-positive bacteria, and 4.3% yeast. During the pandemic, 148 (17.5%) out of 847 blood culture samples exhibited growth, with 31.8% being Gram-negative, 58.1% Gram-positive bacteria, and 10.1% yeast.…”

“…Methicillin resistance in CNS isolates has been shown in studies to range from 40-90.7%. 23 , 26 - 28 …”

“… 28 , 29 The most frequently reported CNS species include Staphylococcus hominis (43.6%), Staphylococcus epidermidis (26.3%), and Staphylococcus haemolyticus (14.8%). 23 …”

“…While bacterial or viral coinfections are rarely observed during the diagnosis of COVID-19, an increase in the duration of hospital stay and the need for ICU admission, along with invasive procedures, leads to an elevated incidence of secondary infections. 22,23 Among HAIs agents, Candida species are significant and rank 3-6 after microorganisms such as Staphylococcus aureus, Acinetobacter spp., Pseudomonas aeruginosa, Enterococcus spp. are known to cause high mortality rates.…”