Is There Any Place for Spleen Stiffness Measurement in Portal Hypertension?

Non‐invasive ménage à trois for the prediction of high‐risk varices: stepwise algorithm using lok score, liver and spleen stiffness

“…found that SS ≥55 kPa rule in both CSPH and EV [21], with very good specificity values. We also found that the same SS value (42.7 kPa) is predictive for both CSPH and large EV, but the performance in a validation cohort was modest (AUROC = 0.633) . The study of Sharma et al .…”

“…Collechia et al found that SS ≥55 kPa rule in both CSPH and EV [21], with very good specificity values. We also found that the same SS value (42.7 kPa) is predictive for both CSPH and large EV, but the performance in a validation cohort was modest (AUROC = 0.633) (43). The study of Sharma et al finds significant differences in SSM values in cirrhotic patients without EV (32 kPa), as compared with those with small EV (49 kPa), large EV (56 kPa) or those that bled (58 kPa)(44).…”

Modification of splenic stiffness on acoustic radiation force impulse parallels the variation of portal pressure induced by transjugular intrahepatic portosystemic shunt

“…The use of splenic stiffness measurement as a non-invasive method to detect the presence of clinically significant portal hypertension 10 or of esophageal varices 13 was already suggested, although the models based on SS for the identification of the patients with large varices need to be fully validated. 36,37 SS has been showed to be useful also in patients with portal hypertension due to portal vein obstruction. 18 In addition to the above applications, our findings support the possibility that the modification of portal pressure could be monitored by SS measurement by ARFI imaging.…”

Spleen transient elastography predicts actuarial survival after liver transplantation

“…Liver TE measurement accurately estimates the presence of advanced fibrosis and cirrhosis in patients with chronic liver disease (4). However, recent studies further showed that spleen stiffness, measured by transient elastography correlates with hepatic venous pressure gradient (5)(6)(7)(8). Therefore, splenic elastography was shown to identify clinically significant portal hypertension (9)(10)(11)(12).…”