2002
DOI: 10.1016/s0378-5122(02)00151-2
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Is there a menopausal medicine? The past the present and the future

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Cited by 8 publications
(4 citation statements)
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“…1998, Brood‐van Zanten et al. 2002, Laborde & Foley 2002, Neves‐e‐Castro 2002). Belief in the benefits of HRT was based on a number of observational epidemiological studies that had shown, for example, that the use of combined hormones during menopause was associated with decreased risk of coronary heart disease averaging 30–50% (Stampfer & Colditz 1991).…”
Section: Introductionmentioning
confidence: 99%
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“…1998, Brood‐van Zanten et al. 2002, Laborde & Foley 2002, Neves‐e‐Castro 2002). Belief in the benefits of HRT was based on a number of observational epidemiological studies that had shown, for example, that the use of combined hormones during menopause was associated with decreased risk of coronary heart disease averaging 30–50% (Stampfer & Colditz 1991).…”
Section: Introductionmentioning
confidence: 99%
“…The risk was considered minimal and mostly related to a small increase in the prevalence of breast cancer (Grady et al 1992, Jó hannesson et al 1995, Grodstein et al 1996, Col et al 1999, Reynolds et al 2002. Until June 2002, the majority of recommendations to women on the use of HRT were therefore that, although the risk/benefit ratio was not known, the prevailing evidence was in favour of its use (Elíasson et al 1998, Brood-van Zanten et al 2002, Laborde & Foley 2002, Neves-e-Castro 2002. Belief in the benefits of HRT was based on a number of observational epidemiological studies that had shown, for example, that the use of combined hormones during menopause was associated with decreased risk of coronary heart disease averaging 30-50% (Stampfer & Colditz 1991).…”
Section: Introductionmentioning
confidence: 99%
“…This period is of major importance to women's life, with important repercussions in social and clinical aspects. The great changes that women undergo during this period usually affect women's quality of life negatively [ 3 ]. Among them, one may highlight alterations that take place as a consequence of the normal aging process, both clinically and behaviorally, such as increased tendency or prevalence of certain diseases, social isolation, and empty nest syndromes, among others [ 2 ].…”
Section: Introductionmentioning
confidence: 99%
“…However, consequences not only related to aging but rather to hypoestrogenism deserve special attention, either due to its burden on public health costs or to women's quality of life. In general, hormonal alterations during menopause transition and postmenopause are strongly related to a series of unpleasant symptoms and complaints [ 3 ], among which the vasomotor symptoms, hot flushes, mood disorders, and specially sleep-related disorders [ 4 ] are remarkable.…”
Section: Introductionmentioning
confidence: 99%