Is There a Gender Difference of Metabolic Syndrome in Hemodialysis?

Abstract

The prevalence of metabolic syndrome is high in hemodialysis. MS is defined by the combination of high blood pressure, dyslipidemia, central obesity and a state of insulin resistance. The aim of this work is to see if there's a difference by gender in the different parameters of metabolic syndrome and in cardiovascular morbidity in our hemodialysis patients. It is a cross-sectional study of 120 patients older than 18 years on hemodialysis. The metabolic syndrome was defined according to the criteria of the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III). A comparison by gender was performed for the following parameters: age, diabetes, hypertension, obesity, dyslipidemia, coronary artery disease and heart failure. Forty chronic hemodialysis patients with metabolic syndrome have been the subject of this study. The sex ratio was 1.88 and the mean age was 55.97 years. Seventy percent had diabetes and 90% were hypertensive. Coronary artery disease was present in 57.5% of cases and heart failure in 52.5% of cases. The study by gender showed no significant difference except for the prevalence of hyper LDL cholesterol. There is a high prevalence of cardiovascular complications in men but a significant difference by gender could not be demonstrated.

Prevalence of Metabolic Syndrome and Associated Factors among Hemodialysis Patients Monitored at the National Teaching Hospital, Hubert Koutoucou Maga in 2015

“…It is similar in the studies of Jalalzadeh (p < 0.001) and Radojica (p = 0.04) [7] [15]. However, in Gorsane's study, diabetes was not associated with metabolic syndrome [10].…”

“…Jalalzadeh observed among hemodialysis patients in Iran in 2011, 28.7% prevalence; Pérez in Spain in 2014, 29% and Maoujoud in Morocco recorded in 2011, 44% [7] [8] [9]. This prevalence within hemodialysis population may reach 70% [10]. Metabolic syndrome triples the risk of developing cardiovascular disease [9] [11], and increases two-fold mortality among hemodialysis patients [12].…”

Detection Levels of Cytokines (IL-6 and IL-18) and Microbial Parameters in Patients with Renal Failure in Diyala Province

“…Results of current study showed the percentage of males more than females with non-significant difference between sex of patients p>0.05 and shown as in table (1). Results of current study show that the percentage of males with renal failure more than females and reasons of it may be due largely to the daily effort after exposed then women, large number of protein consume by men than women, also muscle mass in men than women leads to increase concentration of creatinine in men [17] . In addition, result of current study were compatible with results conducted by [18] which express the male with renal failure more than to female.…”