Is the oncological impact of vascular invasion more important in right colon cancer?

Abstract

Vascular invasion is an unfavorable prognostic factor for the recurrence and systemic metastasis of colon cancer. An interesting study in this issue evaluate the difference in the oncological impact of vascular invasion according to tumor side in colon cancer. The authors suggest that the oncological impact of vascular invasion could be worse in nonmetastatic right colon cancer than in nonmetastatic left colon cancer. Herein, hematoxylin-eosin staining was used to detect vascular invasion. In a recent study, elastin staining could detect more venous invasion. It is expected that the molecular pathologic characteristics of colon cancer can be identified precisely and the oncological outcomes of colon cancer can be improved in the future.

Correlation between color doppler flow pattern and molecular biology in elderly patients with colon cancer

“…However, intratumoral vessels in colon cancer differ from normal physiological vessels [ 18 ]. Colon cancer has the characteristics of irregular shape, disorganization and uneven distribution of blood vessels in the tumor, and the lumen of blood vessels presents an unnatural state [ 19 ]. Spatial distribution and density difference are the pathophysiological basis of CDFI vascular grading technique in detecting colon tumors.…”