Is the need for an arterial resection a contraindication to pancreatic resection for locally advanced pancreatic adenocarcinoma? a case‐matched controlled study

Abstract

Pancreatic resections with AR for adenocarcinoma allowed to obtain a 3-survival rate similar to that of a matched group of patients not requiring AR.

Influence of Perineural Invasion on Survival and Recurrence in Patients with Resected Pancreatic Cancer

“…14 of the remaining 35 studies (Kim et al, 2006;Murakami et al, 2008;Balentine et al, 2010;Chu et al, 2010;Kanda et al, 2010;de Jong et al, 2011;Jamieson et al, 2011;Kneuertz et al, 2011;Maithel et al, 2011;Singal et al, 2011;Chatterjee et al, 2012;Watanabe et al, 2012;Xie et al, 2012;Fisher et al, 2013) were excluded because they were reported by the same institutions as other studies. 21 studies (Ozaki et al, 1999;Mitsunaga et al, 2005;Nakagohri et al, 2006;Pawlik et al, 2007;Kazanjian et al, 2008;Kato et al, 2009;Nagai et al, 2009;Sergeant et al, 2009;Ben et al, 2010;Murakami et al, 2010;Bachellier et al, 2011;Kim et al, 2011;Schiffman et al, 2011;Cheng et al, 2012;Jamieson et al, 2012;Lee et al, 2012;Murata et al, 2012;Sahin et al, 2012;Takahashi et al, 2012;Turrini et al, 2013;Xie et al, 2013) were included in the final meta-analysis, comprising one case matched controlled study and 20 retrospective cohort studies (Table 1). A total of 4459 patients were included in this meta-analysis.…”

“…Involvement of the celiac, hepatic, or superior mesenteric arteries has commonly been considered a contraindication to resection of locally advanced pancreatic cancer (Mollberg et al, 2011). One included study (Bachellier et al, 2011) was reported that 34 patients underwent an extended pancreatic resection with arterial resection. We included the study because it corresponded to "resecected pancreatic cancer".…”

The Role of Vascular Resection in Pancreatic Cancer Treatment

“…Some studies doubted the question whether performing of arterial resection in patients with pancreatoduodenectomy is necessary because the procedure itself is a technical challenge. They confirmed that the arterial resection is possible, but there were not enough data in favor, and that is why it is applied in the context of randomized controlled trials (RCTs) [25].…”

Portal Vein Resection During Pancreatectomy for Pancreatic Head Adenocarcinoma. Scope of Current Opinions and own Experiences

“…The author believes that PVR should become a standard procedure during PD. Furthermore, there are many publications describing more aggressive types of resections in selected groups of patients including arterial resection, but are not considered routine and thus cannot yet be recommended (11,12,13).…”