Is the Degree of Discomfort Caused by Tinnitus in Normal‐Hearing Individuals Correlated with Psychiatric Disorders?

Granjeiro, Ronaldo Campos; Kehrle, Helga Moura; Oliveira, Taciana Sarmento Cardoso de; Sampaio, André Luiz Lopes; Oliveira, Carlos Augusto Costa Pires de

doi:10.1177/0194599812473554

Cited by 31 publications

(50 citation statements)

References 24 publications

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“…In our series a high prevalence (about 60%) of psychological comorbidities among tinnitus patients was found. The prevalence of patients with anxiety was higher, compared with depressive one (45% vs. 26.25% respectively), according to previous reports [8][9] . THI scores show a strong correlation with both values of the subgroups HADS-A and HADS-D. Our findings demonstrate that severity of subjective tinnitus discomfort is strongly related to the psychological distress measured by HADS.…”

Section: Discussionsupporting

confidence: 74%

“…Our results prove that the routine administration of HADS questionnaire, specifically addressed to non-psychiatric patients, is useful in subjects with high risk for developing anxious-depressive symptoms. Accordingly with recent literature, tinnitus patients do not usually meet diagnostic criteria for major depressive disorders but often shows mild psychiatric symptoms, leading to impaired quality of life [4][5][6][7][8][9][10] . HADS is a highly sensitive questionnaire, describing the salient features of psychiatric spectrum.…”

Section: Discussionmentioning

confidence: 99%

“…Its administration may be helpful in improving audiological counselling and addressing of patients to a specific neuropsychiatric evaluation or cognitive-behavioural therapy. In clinical studies 8,9 outcomes significantly differ in terms of both overall prevalence of psychiatric disorder and specific symptoms involved in tinnitus patients. This is probably due to differences in methodological issues (general population studies versus targeted high risk groups of patients; primary care versus tertiary referral hospital), employment of different questionnaires (THI, HADS, VAS) or diagnostic criteria.…”

Section: Discussionmentioning

confidence: 99%

“…It is designed according to the actual conditions of the patient, with a relatively short number of items, thus preventing the patient from losing concentration or answer superficially. For these reasons we preferred the use of HADS, rather than other psychometric scales like BADI (Beck Anxiety and Depression Inventory), employed in analogous studies and first used as a comparison for the statistical validation of THI 8,9 , consisting of a total of 42 items.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Relationship between Subjective Tinnitus Perception and Psychiatric Discomfort

Fetoni¹,

Lucidi²,

Corso³

et al. 2016

The International Tinnitus Journal

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Section: Discussionsupporting

confidence: 74%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Relationship between Subjective Tinnitus Perception and Psychiatric Discomfort

Fetoni¹,

Lucidi²,

Corso³

et al. 2016

The International Tinnitus Journal

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“…This is an important distinction since many paradigms cannot determine, in the same animals, both onset and lasting tinnitus perception, tinnitus pitch, or when specific animals express tinnitus-like behavior [59]. The fact that tinnitus characteristics can also vary in humans [60, 61] emphasizes the need for animal paradigms that can effectively describe a range of characteristics. Thorough assessment of tinnitus development from an acute to chronic status may play a crucial role in pinpointing the fundamental mechanisms underlying tinnitus manifestation.…”

Section: Discussionmentioning

confidence: 99%

A Conditioned Behavioral Paradigm for Assessing Onset and Lasting Tinnitus in Rats

et al. 2016

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Numerous behavioral paradigms have been developed to assess tinnitus-like behavior in animals. Nevertheless, they are often limited by prolonged training requirements, as well as an inability to simultaneously assess onset and lasting tinnitus behavior, tinnitus pitch or duration, or tinnitus presence without grouping data from multiple animals or testing sessions. To enhance behavioral testing of tinnitus, we developed a conditioned licking suppression paradigm to determine the pitch(s) of both onset and lasting tinnitus-like behavior within individual animals. Rats learned to lick water during broadband or narrowband noises, and to suppress licking to avoid footshocks during silence. After noise exposure, rats significantly increased licking during silent trials, suggesting onset tinnitus-like behavior. Lasting tinnitus-behavior, however, was exhibited in about half of noise-exposed rats through 7 weeks post-exposure tested. Licking activity during narrowband sound trials remained unchanged following noise exposure, while ABR hearing thresholds fully recovered and were comparable between tinnitus(+) and tinnitus(-) rats. To assess another tinnitus inducer, rats were injected with sodium salicylate. They demonstrated high pitch tinnitus-like behavior, but later recovered by 5 days post-injection. Further control studies showed that 1): sham noise-exposed rats tested with footshock did not exhibit tinnitus-like behavior, and 2): noise-exposed or sham rats tested without footshocks showed no fundamental changes in behavior compared to those tested with shocks. Together, these results demonstrate that this paradigm can efficiently test the development of noise- and salicylate-induced tinnitus behavior. The ability to assess tinnitus individually, over time, and without averaging data enables us to realistically address tinnitus in a clinically relevant way. Thus, we believe that this optimized behavioral paradigm will facilitate investigations into the mechanisms of tinnitus and development of effective treatments.

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Association between sleep quality and psychiatric disorders in patients with subjective tinnitus in China

Yao

Wang

2016

Eur Arch Otorhinolaryngol

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The study aimed to investigate the relationship between quality of sleep and psychiatric disorders including anxiety and depression in patients with subjective tinnitus. Early intervention is associated with improved therapeutic outcomes. We used Pittsburgh sleep quality index (PSQI), self-rating anxiety scale (SAS), self-rating depression scale (SDS) and tinnitus handicap inventory (THI) in 543 patients [224 male (41.3 %); 319 female (58.7 %)] with subjective tinnitus enrolled in the ENT outpatient clinic from 2013 to 2015. Tinnitus characteristics and hearing status were recorded. A binary step-wise logistic regression analysis was performed. Two hundred cases (36.8 %) including 65 men (32.5 %) and 135 women (67.5 %) were diagnosed with sleep disorders. The PSQI score was the highest in patients with anxiety plus depression. Prolonged sleep latency and daytime dysfunction were positively associated with anxiety and depression. Increased sleep latency score was associated with 1.521- and 1.667-fold increased risk of anxiety and depression. Increase in the daytime dysfunction score was associated with 1.941- and 1.477-fold increases in the risk of anxiety and depression, respectively. Psychiatric and sleep disorders are highly prevalent in patients with subjective tinnitus. The most severe sleep impairment was found in patients with anxiety plus depression, resulting from prolonged sleep latency and severe daytime dysfunction. Acute duration, young people, hearing loss, impaired sleep, and severity of tinnitus were the major risk factors for tinnitus accompanied with anxiety symptoms. Severity of tinnitus and sleep impairment appeared to be the major risk factors of tinnitus accompanied with depression symptoms.

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Is the Degree of Discomfort Caused by Tinnitus in Normal‐Hearing Individuals Correlated with Psychiatric Disorders?

Abstract: This study showed altered OAE in patients with tinnitus and normal hearing. It also demonstrated a positive correlation between the annoyance of tinnitus and anxiety and depression in normal-hearing patients.

Cited by 31 publications

References 24 publications

Relationship between Subjective Tinnitus Perception and Psychiatric Discomfort

Relationship between Subjective Tinnitus Perception and Psychiatric Discomfort

A Conditioned Behavioral Paradigm for Assessing Onset and Lasting Tinnitus in Rats

Association between sleep quality and psychiatric disorders in patients with subjective tinnitus in China

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