Is the CT target sign specific to COVID-19 pneumonia?

Marchiori, Edson; Albuquerque, Jessica; Amorim, Viviane Brandão; Zanetti, Gláucia

doi:10.36416/1806-3756/e20200541

Cited by 6 publications

(6 citation statements)

References 5 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“… “Atoll sign”: Central ground-glass attenuation with peripheral consolidation [ 14 ]. “Bulls-eye sign” or “Target sign” or “Double-halo”: Central nodule or consolidation and peripheral organization rim with ground-glass in between [ 15 ]. “Crazy-paving pattern”: Ground-glass attenuation with septal thickening [ 14 ].…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

COVID-19 in Egypt after a year: the first and second pandemic waves from the radiological point of view; multi-center comparative study on 2000 patients

Samir

El-Abd

Mohamed

et al. 2021

Egypt J Radiol Nucl Med

View full text Add to dashboard Cite

Background One year has passed since the announcement of COVID-19 as a pandemic and two waves had already stricken Egypt. The authors witnessed several atypical radiological features through the second pandemic wave, either early at the active infective stage or delayed at the post-infectious convalescent period. They believed every radiologist should be familiar with these features. Therefore, they performed this comparative study on 2000 Egyptian patients using multi-slice computed tomography (MSCT) to highlight the radiological differences between the first and second pandemic waves and correlate them to the clinical status. Results This random multi-center comparative study was retrospectively conducted on 2000 COVID-19 Egyptian patients; 1000 patients were registered at the first pandemic wave from April 2020 till September 2020, while the other 1000 patients were registered at the second pandemic wave from October 2020 till March 2020. Follow up CT examinations were performed for 49 and 122 patients through the first and second pandemic waves respectively. MSCT examinations were carefully evaluated by four expert consulting radiologists who came to a consensus. Meanwhile, the correlation with the clinical outcome was performed by two consulting pulmonologists. During the second pandemic wave, the prevalence rate of the “crazy-paving” pattern had significantly increased by 1.3 times (P value = 0.002). Additionally, the prevalence rate of the “air-bubble” sign had significantly increased by 1.9 times (P value = 0.02). Similarly, the presence of enlarged mediastinal lymph nodes (> 1 cm in short-axis diameter) had significantly increased by 1.7 times (P value = 0.036). Furthermore, the prevalence rate of pericardial effusion had significantly increased by 2.5 times (P value = 0.003). The above-mentioned signs were correlated to increased clinical severity and higher rates of hospitalization. Unexpectedly, other atypical radiological signs were only encountered through the second pandemic wave, including bronchiectatic changes (2.5%), “head-cheese” pattern (0.8%), cavitation (0.5%), and “bulls-eye” sign (0.2%). The prevalence rate of post-COVID fibrosis had doubled through the second wave but not in a significant way (P value = 0.234). Secondary fungal infection was only encountered throughout the second pandemic wave in four patients. COVID-19 reinfection was encountered in a single patient only during the second pandemic wave. Conclusion After 1 year from the announcement of COVID-19 as a pandemic, the radiological presentation of COVID-19 patients showed some significant differences between its first and second waves.

show abstract

Section: Methodsmentioning

confidence: 99%

“…“Bulls-eye sign” or “Target sign” or “Double-halo”: Central nodule or consolidation and peripheral organization rim with ground-glass in between [ 15 ].…”

Section: Methodsmentioning

confidence: 99%

COVID-19 in Egypt after a year: the first and second pandemic waves from the radiological point of view; multi-center comparative study on 2000 patients

Samir

El-Abd

Mohamed

et al. 2021

Egypt J Radiol Nucl Med

View full text Add to dashboard Cite

show abstract

“…Target signs are well‐known imaging signs of intestinal intussusception but have been limited to reports associated with SARS‐CoV‐2 infection or organizing pneumonia on chest imaging 1 . A target sign consists of a ring‐like opacity and a central nodular opacity.…”

Section: Clinical Imagementioning

confidence: 99%

Target sign of the lung

Kinoshita,

Takata,

Kushima

et al. 2024

Respirology Case Reports

View full text Add to dashboard Cite

show abstract

“…(4) When only with one or two ringlike opacities, this sign is not specific to COVID-19, and the differential diagnosis includes conditions other than organizing pneumonia, such as metastasis and post-radiofrequency ablation zone. (5,6) However, the manifestation with multiple concentric ring-like opacities (Figure 1) has only been reported so far in patients with COVID-19 pneumonia. (4) We emphasize the importance of familiarizing radiologists with imaging findings of COVID-19 pneumonia to contribute to its diagnostic suspicion.…”

mentioning

confidence: 99%