2016
DOI: 10.5867/medwave.2016.6379
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Is the addition of aminoglycosides to beta-lactams in cancer patients with febrile neutropenia needed?

Abstract: It is still controversial if the combined use of beta-lactam antibiotics and aminoglycosides has advantages over broad-spectrum beta-lactam monotherapy for the empirical treatment of cancer patients with febrile neutropenia. Searching in Epistemonikos database, which is maintained by screening 30 databases, we identified three systematic reviews including 14 pertinent randomized trials. We combined the evidence using meta-analysis and generated a summary of findings table following the GRADE approach. We concl… Show more

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“…Los antibióticos utilizados al ingreso son los mismos que se utilizan en las guías terapéuticas a nivel (22) mundial . No se utilizó factor estimulante de colonia de granulocitos por no disponerse del mismo a nivel (23) hospitalario y por tratarse muchas veces de neutropenias transitorias .…”
Section: Discussionunclassified
“…Los antibióticos utilizados al ingreso son los mismos que se utilizan en las guías terapéuticas a nivel (22) mundial . No se utilizó factor estimulante de colonia de granulocitos por no disponerse del mismo a nivel (23) hospitalario y por tratarse muchas veces de neutropenias transitorias .…”
Section: Discussionunclassified