Is Sleep Deprivation Associated With Adverse Pregnancy Outcomes? [22M]

Abstract

INTRODUCTION: The purpose of this study was to evaluate the association between measures of sleep deprivation (SD) and adverse pregnancy outcomes. METHODS: A screening questionnaire which included novel items intended to assess sleep deprivation, was administered at the time of prenatal care; this was a secondary analysis of participants enrolled (2010-2012). SD was defined as a 3 hour or more difference between weekday and weekend self-reported sleep duration. This analysis received an IRB exemption. RESULTS: Of 1172 women, 17.41% (n=204) had SD. Women with SD were more likely to have large for gestational age (LGA) babies (6.5% vs. 2.99%, P=.015) and babies admitted to the neonatal intensive care unit (NICU) (21.1% vs. 15.4%, P=.048). Women who reported falling asleep while driving were more likely to have gestational hypertension (gHTN) (18.6% vs. 9.3%, P=.030), preeclampsia (PreE) (27.1% vs. 13.8%, P=.010), PreE with severe features (18.8% vs. 8.68%, P=.017) and to experience adverse composite obstetric outcomes (64.7% vs. 50%, P=.040). Women who reported napping were more likely to have PreE with severe features (11.1% vs. 7.59%, P=.049), preterm birth (PTB) (16.6% vs. 9.71%, P=.001), and NICU admission (20.9% vs. 14.4%, P=.005). Women who reported napping more than 3x/week were more likely to have gHTN (12.0% vs. 8.12%, P=.024), PTB (16.0% vs. 10.3%, P=.003), and adverse composite obstetric outcomes (54.0% vs. 48.3%, P=.047). CONCLUSION: Sleep deprivation, falling asleep while driving, and napping are associated with various adverse obstetric outcomes and composite obstetric outcomes. Further research into the effects of sleep deprivation during pregnancy is warranted.