Is Sjogren's syndrome a risk factor/contraindication for dental implants? An umbrella review

Abstract

Introduction There have been concerns that longstanding oral dryness secondary to Sjogren's syndrome may increase the risk of failure of dental implants. Aims The aim of the present study was to determine the level of methodological quality of systematic reviews that evaluated the effectiveness of dental implants in patients diagnosed with Sjogren's syndrome. Methods and results Databases of PubMed/Medline, LILACS, Science Direct and Dare Cochrane to October 2020 were evaluated. A total of 833 articles were initially identified but following use of appropriate inclusion and exclusion criteria 4 papers were identified for detailed analysis. An eventual study sample comprised 722 implants placed in 189 patients with a 95.22% success rate, the minimum follow‐up time was 45.2 ± 23.8 months and the maximum 125.5 months. The studies were assessed for their methodological quality by the AMSTAR 2 tool, in which 3 had critically low quality and one low quality. Conclusion Oral rehabilitation with dental implants in patients with Sjogren's syndrome seems to have a high success rate; however, the low quality of relevant reports highlights the need for primary and secondary studies with better methodological design in order to reduce bias and provide reassurance for this treatment option.

Impact of local predisposing/precipitating factors and systemic drivers on peri‐implant diseases

“…136 • Autoimmune/inflammatory/rheumatoid/skin diseases, 128 especially Sjogren's syndrome. 137,138 • Genetics/epigenetics. 116,[139][140][141] • HIV-1.…”

Dental implants in dentate primary and secondary Sjögren's syndrome patients: A multicenter prospective cohort study

“…To date, no prospective clinical trials have been published in which the success and survival of implants in patients with SS were investigated and compared to healthy subjects. Only retrospective studies and case series reported on the use of dental implants in patients with SS, often with favorable outcomes (Albrecht et al, 2016 ; Almeida et al, 2017 ; Barros et al, Barros et al, 2021 ; Chrcanovic et al, 2019 ; Korfage et al, 2016 ), but also with less favorable outcomes such as an above average loss of implants (Isidor et al, 1999 ; Payne et al, 1997 ). Therefore, this study aims to prospectively investigate the clinical performance and patient‐reported outcomes of dental implants in dentate patients with SS compared to subjects without SS up to 18 months after placement of the suprastructure.…”