Abstract:Background: To study the effect of testosterone treatment on markers of inflammation in hypogonadal men with MS.Methods: 20 men with MS (IDF criteria) and LOH (total testosterone (TT) < 11 nmol/l) received 3 injections of testosterone undecanoate (Nebido) or placebo. Patients were divided into two groups according to TT levels 12 weeks after the third injection of Nebido/placebo: in group 1 (n = 13) TT was normalized to 15.75 [13.5-17.3] nmol/l and in group 2 (n = 7), TT was not normalized (8.3 [6.5-10.2] nmol… Show more
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