“…The GO enrichment analysis for the DMRs indicated that the genes were mainly enriched in the GO terms, including HES4, PRKCZ,SKI,PRDM16,ALPL,RUNX3,TAL1,TTLL7,BARHL2,OLFM3,NFYC,TBX15,LMX1A,TNFRSF4,AJAP1,SYTL1,OPRD1,PTPRU,PRRX1,ELF3,PROX1, (Table 4). Among these, we screened HLA-G (P = 1.86E−30), HLA-E (P = 9.42E−11), and PRDM16 (P = 1.86E−30), which are closely related to embryonic development, as candidate genes of RM (Gelmini et al, 2016;Horn et al, 2011;Verloes et al, 2017).…”