Is Sacral Nerve Modulation a Good Option for Fecal Incontinence in Men?

Brochard, Charlène; Mège, Diane; Bridoux, Valérie; Meurette, G.; Damon, Henri; Lambrescak, Elsa; Faucheron, Jean‐Luc; Trilling, Bertrand; Lehur, Paul‐Antoine; Wyart, Vincent; Sielezneff, I.; Mion, François; Etienney, Isabelle; Leroi, Anne‐Marie; Siproudhis, L.

doi:10.1111/ner.13017

Cited by 6 publications

(8 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results indicating that sex is a predictor of SNM outcome confirmed a previous study showing that both short-and long-term success rates of SNM for FI tend to be less favorable in men than in women, perhaps due to the specific pathophysiopathology of FI in men. 25 Even if this result needs to be confirmed by others, it does not seem surprising that patients who have failed previous surgeries are less likely to be improved by a new therapy. It should be noted that, at the beginning of the implantation period (ie, January 1998), most of the surgeons were not perfectly trained in SNM.…”

Section: Discussionmentioning

confidence: 97%

“…The follow-up included an assessment of CCIS, the use of additional FI treatments, and the recording of adverse events, including surgical revision and definitive explantation at 1 to 3 years, 3 to 5 years, and 10 years post-implantation. Despite the retrospective nature of the study, some standardization of the follow-up (ie, schedules of the visits, scores) was possible because all the centers involved in the present study had performed studies with a similar follow-up design 24,25 . In addition, in one of our publications, we set out the post-implantation follow-up protocol for our patients (data to collect and intervals of follow-up visits) 26 .…”

Section: Methodsmentioning

confidence: 99%

“…Despite the retrospective nature of the study, some standardization of the follow-up (ie, schedules of the visits, scores) was possible because all the centers involved in the present study had performed studies with a similar follow-up design. 24,25 In addition, in one of our publications, we set out the post-implantation follow-up protocol for our patients (data to collect and intervals of follow-up visits). 26 Like previous studies, 25,27,28 the primary treatment outcome was defined as favorable if the patient reported a therapeutic benefit from SNM and did not consider SNM treatment discontinuation or additional therapy beyond the use of bowel transit-modifying medications.…”

Section: Follow-up and Definitionsmentioning

confidence: 99%

“…24,25 In addition, in one of our publications, we set out the post-implantation follow-up protocol for our patients (data to collect and intervals of follow-up visits). 26 Like previous studies, 25,27,28 the primary treatment outcome was defined as favorable if the patient reported a therapeutic benefit from SNM and did not consider SNM treatment discontinuation or additional therapy beyond the use of bowel transit-modifying medications. The treatment outcome was defined as unfavorable if the patient was not satisfied with SNM and required an alternative treatment (medical treatment excluded) such as stoma formation or if the patient had switched off the IPG or had it surgically removed.…”

Section: Follow-up and Definitionsmentioning

confidence: 99%

See 3 more Smart Citations

Ten-year Evaluation of a Large Retrospective Cohort Treated by Sacral Nerve Modulation for Fecal Incontinence

Desprez¹,

Damon

Meurette³

et al. 2020

Annals of Surgery

Self Cite

View full text Add to dashboard Cite

Objective:The aim of this study was to assess the effectiveness of sacral nerve modulation (SNM) in a large cohort of patients implanted for at least 10 years, quantify adverse event rates, and identify predictive factors of long-term success.Summary Background Data:Few studies have evaluated the long-term success of SNM.Methods:Data collected prospectively from patients implanted for fecal incontinence (FI) in 7 French centers between January 1998 and December 2008 were retrospectively analyzed. Patient FI severity scores were assessed before and 10 years after implantation. The main evaluation criterion was the success of SNM defined by the continuation of the treatment without additional therapies. The secondary evaluation criteria were the rate of device revisions and explantations. Preoperative predictors of success at 10 years were sought.Results:Of the 360 patients (27 males, mean age: 59 ± 12 years) implanted for FI, 162 (45%) had a favorable outcome 10 years post-implantation, 115 (31.9%) failed, and 83 (23.1%) were lost to follow-up. The favorable outcome derived from the time-to-event Kaplan-Meier curve at 10 years was 0.64 (95% CI 0.58–0.69). FI severity scores were significantly better 10 years post-implantation compared to preimplantation (7.4 ± 4.3 vs 14.0 ± 3.2; P < 0.0001). During the 10-year follow-up, 233 patients (64.7%) had a surgical revision and 94 (26.1%) were explanted. A history of surgery for FI and sex (male) were associated with an increased risk of an unfavorable outcome.Conclusions:Long-term efficacy was maintained in approximately half of the FI patients treated by SNM at least 10 years post-implantation.

show abstract

Section: Discussionmentioning

confidence: 97%

Section: Methodsmentioning

confidence: 99%

Section: Follow-up and Definitionsmentioning

confidence: 99%

Section: Follow-up and Definitionsmentioning

confidence: 99%

See 2 more Smart Citations

Ten-year Evaluation of a Large Retrospective Cohort Treated by Sacral Nerve Modulation for Fecal Incontinence

Desprez¹,

Damon

Meurette³

et al. 2020

Annals of Surgery

Self Cite

View full text Add to dashboard Cite

show abstract

“…In fact, several studies, have shown that the effectiveness of SNM in treating fecal incontinence ranges between 45 and 90% [ 8 , 9 ] of the patients according to the follow-up duration, sex and type of incontinence, but little is known on the very long-term outcome of these patients. In the common clinical practice, the percentage of incontinent patients with SNM implant undergoing surgical replacement of exhaust IPG (implantable pulse generator) after more than 5 years from the implant is often lower than expected and no studies have specifically addressed this issue.…”

Section: Introductionmentioning

confidence: 99%

Ageing with sacral nerve modulation for fecal incontinence: how many patients get benefit after more than 10 years?

et al. 2022

View full text Add to dashboard Cite

Sacral nerve modulation (SNM) has represented a major advancement in the minimally invasive management of patients with fecal incontinence (FI). Although the success rate in the short–medium term has widely been demonstrated, the very long-term outcomes are poorly investigated. This study aims to assess the effectiveness of SNM in a cohort of patients with a follow-up longer than 10 years. Clinical records of patients submitted to SNM for FI in our tertiary referral colorectal Unit between 1998 and 2010 were retrospectively reviewed looking for status of the implantable pulse generator (IPG), follow-up duration, severity of FI by the St Marks’ score and quality of life. 58 patients fulfilled the entry criteria and 36 (58%, median follow-up, 12 years) accepted to take part to the telephone interview, while 22 (38%) were lost to the follow-up. Nineteen patients had their IPG removed (Group A) while 17 (27%) had the SNM still active after a median follow-up of 13 years (Group B). In the group A, the median baseline St Marks’ score was 13 and did not change after the IPG removal. In group B, the median baseline St Marks’ score was 14, at last IPG substitution, it was of 7 and at the last follow-up dropped to 4. In the group A, the median SF-12 physical and mental scores did not change significantly while they improved significantly in group B. A progressive deterioration of the success rate of SNM with the time has been documented after a very long-term follow-up.

show abstract

Efficacy and safety of sacral nerve modulation for faecal incontinence after pelvic radiotherapy

Mège

Meurette²,

Trilling³

et al. 2020

Radiotherapy and Oncology

View full text Add to dashboard Cite

Is Sacral Nerve Modulation a Good Option for Fecal Incontinence in Men?

Cited by 6 publications

References 31 publications

Ten-year Evaluation of a Large Retrospective Cohort Treated by Sacral Nerve Modulation for Fecal Incontinence

Ten-year Evaluation of a Large Retrospective Cohort Treated by Sacral Nerve Modulation for Fecal Incontinence

Ageing with sacral nerve modulation for fecal incontinence: how many patients get benefit after more than 10 years?

Efficacy and safety of sacral nerve modulation for faecal incontinence after pelvic radiotherapy

Contact Info

Product

Resources

About