Is nocturnal enuresis a predisposing factor for the overactive bladder?

Abstract

Background/aims: To perform a limited observational study to ascertain whether there is statistical support that nocturnal enuresis (NE) is a predisposing factor in the development of overactive bladder (OAB). Materials and methods: The authors recruited patients diagnosed with OAB over a period of twelve months, and those who declared a history of NE were asked additional questions regarding the features of their NE. Results: A total of 285 patients were diagnosed with overactive bladder, and 98 (34.38%) of them had previously displayed NE symptoms that had diminished before reaching the median age of 9.83. Separation of patients by sex revealed a male majority (58.16%). Additionally, most patients had urban origins (75.51%). The median time span from remission of NE to diagnosis of OAB was 24.79 years, and the median age at which patients began to suffer was 31.80 years. Behavioural factors (smoking, alcohol consumption) and psychological and infectious factors (past history of urinary tract infection) were identified at varying degrees. Conclusions: The presence of NE in a third of the patients who in time developed OAB and the earlier onset of OAB for these patients suggests a causal physio-pathological relationship between NE and OAB. The preponderance of urban patients confirm the existence of acquired urban triggering factors of OAB (nutritious, social, or professional). Keywords: Nocturnal enuresis, Overactive bladder, Predisposing cause, Risk factors.

Socio Behavioral Factors Associated with Nocturnal Enuresis among Primary School Children in Abo Homous, Elbehira, Egypt

“…Concerning school performance, the current study revealed that the prevalence of NE among primary school children had a significant association with school performance. This association between prevalence of NE and school performance is more or less a similar findings with those obtained from other studies conducted in South of Egypt, Saudi Arabia, India and Nigeria [11,19,21].…”

“…The present study reported a significant association between low socioeconomic level and NE prevalence among primary school children. This result was matching with that of other studies carried out in South Egypt and Benha .In addition, other studies conducted in India and Pakistan revealed that prevalence rate of NE is relatively higher in lower socio-economic levels [4,11,16,19].…”

“…Children with NE and nocturnal polyuria differ in terms of hemodynamics and autonomic activation at night compared to healthy ones. Children with NE often suffer sleep disordered breathing, as well as disturbed sleep due to awakenings and arousals [11,[19][20][21].…”

Prevalence, Risk Factors, and Psychological Effects of Overactive Bladder in Chinese University Students

“…A separate study showed that PNE is related to OAB in children [ 22 ]. Research has indicated that one-third of patients with OAB have PNE, which may be due to involuntary detrusor activity in patients with PNE [ 23 ].…”