Is motor imagery different in catatonic schizophrenia?

Zaytseva, Yuliya; Morozova, Alexandra; Bendova, Marie; Garakh, Zhanna

doi:10.1002/pchj.155

Cited by 3 publications

(2 citation statements)

References 7 publications

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“…A previous speculative paper by Pridmore et al suggested that pathologically handled MNS-generated representations, especially in IFG, might be involved in this dysfunction ( 129 ). Indeed, this was in line with the findings of the study of Zaytseva et al ( 101 ) where the authors reported altered mu rhythm suppression in the right frontal and central brain regions in patients with catatonic schizophrenia. More studies on catatonic patients in the future are suggested to further evaluate the validity of this finding.…”

Section: Discussionsupporting

confidence: 91%

The mirror mechanism in schizophrenia: A systematic review and qualitative meta-analysis

et al. 2022

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BackgroundMirror neuron system (MNS) consists of visuomotor neurons that are responsible for the mirror neuron activity (MNA), meaning that each time an individual observes another individual performing an action, these neurons encode that action, and are activated in the observer's cortical motor system. Previous studies report its malfunction in autism, opening doors to investigate the underlying pathophysiology of the disorder in a more elaborate way and coming up with new rehabilitation methods. The study of MNA function in schizophrenia patients has not been as frequent and conclusive as in autism. In this research, we aimed to evaluate the functional integrity of MNA and the microstructural integrity of MNS in schizophrenia patients.MethodsWe included case-control studies that have evaluated MNA in schizophrenia patients compared to healthy controls using a variety of objective assessment tools. In August 2022, we searched Embase, PubMed, and Web of Science for eligible studies. We used an adapted version of the NIH Quality Assessment of Case-Control Studies tool to assess the quality of the included studies. Evidence was analyzed using vote counting methods of the direction of the effect and was tested statistically using the Sign test. Certainty of evidence was assessed using CERQual.ResultsWe included 32 studies for the analysis. Statistical tests revealed decreased MNA (p = 0.002) in schizophrenia patients. The certainty of the evidence was judged to be moderate. Investigations of heterogeneity revealed a possible relationship between the age and the positive symptoms of participants in the included studies and the direction of the observed effect.DiscussionThis finding contributes to gaining a better understanding of the underlying pathophysiology of the disorder by revealing its possible relation to some of the symptoms in schizophrenia patients, while also highlighting a new commonality with autism.Systematic review registrationPROSPERO identifier: CRD42021236453.

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Section: Discussionsupporting

confidence: 91%

The mirror mechanism in schizophrenia: A systematic review and qualitative meta-analysis

et al. 2022

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“…Zaytseva et al () describe a case in which the reference to one's own body is lost; such a loss indicates that under normal circumstances, body ownership has to be neurally constructed, as a function or phenomenon can only be lost if it exists, and an observation from one case alone is already sufficient for such a statement. In two cases with catatonic schizophrenia (Zaytseva, Morozova, Bendova, & Garakh, ) using an electroencephalographic indicator of the mu rhythm, the differential modulation of motor imaging compared to other psychiatric patients is shown, again disclosing a new phenomenon. It is, however, not only patients in whom “harvesting serendipity” can be used as an exploratory research tool to expand our knowledge about the mental machinery.…”

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confidence: 94%