Background: A new, self-contained, digital, continuous pump-driven chest drainage system is compared for the first time in a Randomized Control Trial to a traditional wall-suction system in cardiac surgery.Methods: 120 adult elective cardiac patients undergoing CABG and/or valve surgery were randomized to the study or control group. Both groups had similar pre/intra-operative demographics: age 67.8 vs. 67.0 years, Euroscore 2.3 vs. 2.2 and BSA 1.92 vs. 1.91 m2. Additionally, a satisfaction assessment score was performed by 52 staff members.Results: Given homogenous intra-operative variables, total chest-tube drainage was comparable among groups (566 vs. 640 ml; ns), but the study group showed more efficient fluid collection during the early post-operative phase (p = 0.006 and p = 0.01) due to continuous suction compared to 11.5 minutes off-suction time in the control group. Blood, cell saver transfusions and post-operative hemoglobin values were similar in both groups. The study group experienced drain removal after 29.8 vs 38.4 hours in the control group (ns). Seven crossovers from the Study to the Control group were registered but no patient had drain-related complications.Conclusion: The new, self-contained, digital, continuous pump-driven drainage system showed better early drainage of the chest cavity and was as reliable as conventional systems. Quicker drain removal might impact on ICU stay and reduce costs. Additional advantages are portable size, battery operation, patient mobility, noiseless function, digital indications and alarms. The satisfaction assessment of the new system by the staff revealed a higher score when compared to the traditional wall suction chest drainage system. This Randomized Control Trial was retrospectively registered on June 7, 2019 under ISRCTN 14884587. https://doi.org/10.1186/ISRCTN14884587