Is Long-Term Follow-Up Mandatory for Stage I Oral Tongue Cancer?

Prognosticators and Management of Oral Tongue Squamous Cell Carcinoma

“…About the surgical margins in this study, (37.7%) were negative, (11.5%) were positive, and only (1.4%) were closed, in contrast to Nootan Kumar Shukla et al who found in their study that (97.5%) of the surgical margins were negative and only (2.4%) were positive [18], also Snehal G et al who found that (89%) of the patients in his study had negative surgical margins and only (10%) of them had positive surgical margins [24]. Concerning perineural invasion the authors found it in (21.7%) of the patients in our study and (65.2%) did not have a perineural invasion, in agreement to Amal Isaiah et al whose findings were closely similar to ours in which they found that (8.9%) of the patients in his study had perineural invasion and (91.1%) did not [25], in contrast to Snehal G et al who found that (85%) of the patients in their study had perineural invasion with only (15%) of them did not have it [24].…”

“…Concerning extranodal invasion (13%) of the patients in our study experienced it while (73.9%) did not have it, in similar findings to Nootan Kumar Shukla et al who found that (26%) of the patents in their study had extranodal invasion were the rest of them did not experience it [18], also Sohail Awan et al found that (25.6%) of the patients in their study had extranodal invasion while the rest of the patients were clear of it [26]. About the microscopic depth of invasion (52.2%) of the patient in this study had a tumor that was > or equal to 4 mm deep, (10.1%) had a tumor that was < 4 mm deep, and only (1.4%) of the patients having a tumor that was <4 mm deep, Snehal G et al had closely similar findings to ours in that he found that (79%) of the patients in his study had a tumor that was >4 mm deep and only (21%) of the patient's tumor was < 4 mm deep [24], in contrast to Amal Isaiah et al who found that (63.4%) of the patients in their study had <3 mm deep tumor with only (35.7%) of the patient having a >3 mm deep tumor [25]. Furthermore (79.3%) of the patients in this study were found to have it while only (18.8%) of them were clear of any pathologic lymph nodes, in closely similar findings to Nootan Kumar Shukla who found that (56.4%) of the patients in his study had positive pathologic lymph nodes with the rest being clear of it [17], in contrast to Tao Zbang et al who found that only (9.2%) of the patients in his study had positive pathologic lymphnodes [27].…”

“…surgery and radiotherapy respectively, in closely similar findings to Jeffrey C et al who found that (7.4%) of the patients in their study got treated with radiotherapy for the recurrence [25], in contrast to Amal Isaiah et al who found that (50%) of the patients in her study underwent surgical treatment for recurrence [25]. Regarding the mortality of the disease in this study (55%) of the patients died while (45%) of them are still alive, in contrast to Amal Isaiah et al who found that the overall survival rate of the patients in their study was (89%) [25], also Nootan Kumar Shukla et al who found that the overall survival rate for the patients in their study was (78.6%) [17].…”

Prognosticators and Management of Oral Tongue Squamous Cell Carcinoma

“…Concerning extranodal invasion (13%) of the patients in our study experienced it while (73.9%) did not have it, in similar findings to Nootan Kumar Shukla et al who found that (26%) of the patents in their study had extranodal invasion were the rest of them did not experience it [18], also Sohail Awan et al found that (25.6%) of the patients in their study had extranodal invasion while the rest of the patients were clear of it [26]. About the microscopic depth of invasion (52.2%) of the patient in this study had a tumor that was > or equal to 4 mm deep, (10.1%) had a tumor that was < 4 mm deep, and only (1.4%) of the patients having a tumor that was <4 mm deep, Snehal G et al had closely similar findings to ours in that he found that (79%) of the patients in his study had a tumor that was >4 mm deep and only (21%) of the patient's tumor was < 4 mm deep [24], in contrast to Amal Isaiah et al who found that (63.4%) of the patients in their study had <3 mm deep tumor with only (35.7%) of the patient having a >3 mm deep tumor [25].…”

Molecular prognosticators in clinically and pathologically distinct cohorts of head and neck squamous cell carcinoma—A meta-analysis approach

“…In tongue and laryngopharyngeal cancers, advanced stage of the disease signifies poor prognosis. Nevertheless, studies have also shown a subset of early stage patients that have an extremely poor prognosis [65,66]. Biomarkers that can further classify these patients based on outcome can be immensely valuable in this context.…”