Is left ventricular diastolic dysfunction independent from presence of hypertension in metabolic syndrome? An echocardiographic study

Aksoy, Sukru; Durmuş, Gündüz; Özcan, Kazım Serhan; Toprak, Ercan; Gürkan, Ufuk; Öz, Dilaver; Çanga, Yiğit; Karataş, Baran; Duman, Dursun

doi:10.1016/j.jjcc.2014.01.002

Cited by 16 publications

(9 citation statements)

References 33 publications

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“…In modern imaging studies using echocardiography, MRI, cardiac CT, and positron emission tomography, MetS has been shown to be closely related to increased epicardial adipose tissues 223 ; increased visceral fat 224 ; increased ascending aortic diameter 225 ; high-risk coronary plaque features, including increased necrotic core 226 ; impaired coronary flow reserve 227 ; abnormal indexes of LV strain 228 ; LV diastolic dysfunction 229 ; LV dyssynchrony 230 ; and subclinical RV dysfunction. 231…”

Section: Complicationsmentioning

confidence: 99%

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Tsao¹,

Aday²,

Almarzooq³

et al. 2022

Circulation

3,064

2,336

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Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, heart failure, valvular disease, venous disease, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). Methods: The American Heart Association, through its Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current information available in the annual Statistical Update. The 2022 Statistical Update is the product of a full year’s worth of effort by dedicated volunteer clinicians and scientists, committed government professionals, and American Heart Association staff members. This year’s edition includes data on the monitoring and benefits of cardiovascular health in the population and an enhanced focus on social determinants of health, adverse pregnancy outcomes, vascular contributions to brain health, and the global burden of cardiovascular disease and healthy life expectancy. Results: Each of the chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. Conclusions: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.

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Section: Complicationsmentioning

confidence: 99%

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Tsao¹,

Aday²,

Almarzooq³

et al. 2022

Circulation

3,064

2,336

View full text Add to dashboard Cite

show abstract

“…6 The LV diastolic and systolic dysfunction demonstrated by the myocardial performance index (MPI or Tei index) in patients with MetS was associated with a subclinical cardiac 7 In other studies, the MetS was linked to the presence of LV diastolic dysfunction. 8,9 The evaluation of myocardial mechanics by conventional echocardiography and tissue Doppler imaging (TDI) is load-and angle-dependent. Hence, some recent studies have used two-dimensional speckle tracking echocardiography (2D-STE) to assess the myocardial function in patients with MetS.…”

Section: Introductionmentioning

confidence: 99%

Subclinical systolic and diastolic dysfunctions in patients with metabolic syndrome and angiographically normal coronary arteries: An echocardiographic study

Samiei

Bayat

Firouzi

et al. 2017

J of Clinical Ultrasound

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“…The neurological long-term implications of hypertension consist in degrading brain functions including ischemic stroke, white matter alterations, advanced volume losses in hippocampi and frontal lobes, neuroinflammation, oxidative stress, and abnormal brain lipid metabolism (Yates, Sweat, Yau, Turchiano, & Convit, 2012). MetS and hypertension have mutually potentiating relations, because hypertension in MetS aggravates diastolic dysfunction by impairing vascular reactivity (Aksoy, Durmus, Ozcan, Toprak, & Duman, 2014).…”

mentioning

confidence: 99%

Trait anxiety but not state anxiety level associates with biomarkers for hypertension in the metabolic syndrome

2016

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Various studies link hypertension with anxiety; however, it remains unclarified if such relations are present in the metabolic syndrome (MetS). We studied cross-sectionally the interrelations of self-reported anxiety (Spielberger STAI), and MetS components in MetS patients. We investigated a nationally sampled treatment cohort for MetS with familial Type 2 diabetes risk. N = 101 patients fulfilling International Diabetes Federation criteria for MetS participated. Both laboratory and nonlaboratory measures were included. Structural equation models (SEM) were adjusted. The final SEM had an R(2) = .998 with the obesity component linking to waist, BMI, and degree of adiposity, and the hypertension component linking to systolic blood pressure, pulse pressure, total cholesterol, and trait anxiety. For state anxiety, no significant regressive causal path could be estimated. SEM supports the assumption of an interaction of pulse pressure, systolic blood pressure, cholesterol metabolism, and high trait anxiety in the pathophysiology of hypertension in MetS.

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Is left ventricular diastolic dysfunction independent from presence of hypertension in metabolic syndrome? An echocardiographic study

Abstract: These findings support the idea that LVDD may develop in patients with MetS even in the absence of hypertension. In addition, co-existence of hypertension with MetS contributes to further worsening of diastolic functions.

Cited by 16 publications

References 33 publications

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Subclinical systolic and diastolic dysfunctions in patients with metabolic syndrome and angiographically normal coronary arteries: An echocardiographic study

Trait anxiety but not state anxiety level associates with biomarkers for hypertension in the metabolic syndrome

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