2023
DOI: 10.1016/j.neurad.2022.03.009
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Is it safe to discontinue antiplatelet medication after stent-assisted coil embolization? If so, when is the best time?

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Cited by 5 publications
(12 citation statements)
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“…Therefore, they also suggested that it may be safe to discontinue antiplatelet agents after SACE in patients at low risk for ischemia, and the optimal time to discontinue might be around 18-36 months after SACE. 11) The risk of cerebral infarction according to the period of DAPT use was 273 times higher (p=0.035) in patients who used DAPT for over 13 months than in other groups, which is contrary to the established fact. This group continued to use DAPT for over 13 months, which is longer than the typical period because cerebral atherosclerosis was thought to be very severe.…”
Section: Discussionmentioning
confidence: 76%
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“…Therefore, they also suggested that it may be safe to discontinue antiplatelet agents after SACE in patients at low risk for ischemia, and the optimal time to discontinue might be around 18-36 months after SACE. 11) The risk of cerebral infarction according to the period of DAPT use was 273 times higher (p=0.035) in patients who used DAPT for over 13 months than in other groups, which is contrary to the established fact. This group continued to use DAPT for over 13 months, which is longer than the typical period because cerebral atherosclerosis was thought to be very severe.…”
Section: Discussionmentioning
confidence: 76%
“…It is a common recommendation to maintain MAPT for the rest of one’s life after SACE. However, many researchers have questioned whether the maintenance of MAPT for a lifetime in patients undergoing SACE without vasculopathy such as atherosclerosis is a good choice, and there is an opinion that MAPT can be stopped after a certain period of time [ 7 , 11 ].…”
Section: Introductionmentioning
confidence: 99%
“…Kim et al suggested that longer-term DAPT (>9 months) should be considered after stent-assisted coil embolization for unruptured intracranial aneurysms, although its efficacy remains to be clarified ( 10 ). Noah Hong et al ( 3 ) suggested that the optimal time to discontinue might be ~18–36 months after stent-assisted coil embolization. Large cohort-based studies or randomized clinical trials are warranted to confirm these results.…”
Section: Discussionmentioning
confidence: 99%
“…Flemming et al (1) assumed that the incidence was <0.05%, while Ince et al (2) revealed that VBD was detected in ∼2.06% of the first-ever stroke population. Patientswith VBD commonly present with ischemic stroke, intracranial hemorrhage, and compression of the brainstem and/or cranial nerves (3)(4)(5)(6)(7)(8)(9), which could lead to high rates of morbidity and mortality (10). Among endovascular treatments, stent-assisted coil embolization is one of the main treatment modalities for VBD.…”
Section: Introductionmentioning
confidence: 99%
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