Is it Possible to Work together in Latin America? Creation of a Latin American Consortium (CLEHOP)

Freigeiro, D; Arancibia, A. M. Muñoz; Dibar, E; Contreras, Alberto; García, Juan Carmelo García; Castellanos, Mauricio

doi:10.1055/s-0034-1371143

Cited by 2 publications

(1 citation statement)

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“…[30][31][32] GATLA has developed multiple international collaborative relationships, including codevelopment of protocols with the International Berlin-Frankfurt-Munster (I-BFM) group 33,34 and the International Consortium for Childhood Acute Promyelocytic Leukemia. 35 In 2015, GATLA assisted in the founding of the multinational clinical trial consortium Consorcio Latinoamericano de Enfermedades Hematooncol ógicas Pedi átricas (CLEHOP), [36][37][38] which has created several of its own collaborative clinical trial protocols. 39,40 Brazil has been a major contributor to pediatric oncology through the Sociedade Brasileira de Oncologia Pedi átrica (SOBOPE) founded in 1981.…”

Section: Pediatric Oncology Clinical Trial Collaborative Groups By Re...mentioning

confidence: 99%

Mapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage

Major

Palese

Ermis

et al. 2022

JCO Global Oncology

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PURPOSE The global pediatric oncology clinical research landscape, particularly in Central and South America, Africa, and Asia, which bear the highest burden of global childhood cancer cases, is less characterized in the literature. Review of how existing pediatric cancer clinical trial groups internationally have been formed and how their research goals have been pursued is critical for building global collaborative research and data-sharing efforts, in line with the WHO Global Initiative for Childhood Cancer. METHODS A narrative literature review of collaborative groups performing pediatric cancer clinical research in each continent was conducted. An inventory of research groups was assembled and reviewed by current pediatric cancer regional and continental leaders. Each group was narratively described with identification of common structural and research themes among consortia. RESULTS There is wide variability in the structure, history, and goals of pediatric cancer clinical trial collaborative groups internationally. Several continental regions have longstanding endogenously-formed clinical trial groups that have developed and published numerous adapted treatment regimens to improve outcomes, whereas other regions have consortia focused on developing foundational database registry infrastructure supported by large multinational organizations or twinning relationships. CONCLUSION There cannot be a one-size-fits-all approach to increasing collaboration between international pediatric cancer clinical trial groups, as this requires a nuanced understanding of local stakeholders and resources necessary to form partnerships. Needs assessments, performed either by local consortia or in conjunction with international partners, have generated productive clinical trial infrastructure. To achieve the goals of the Global Initiative for Childhood Cancer, global partnerships must be sufficiently granular to account for the distinct needs of each collaborating group and should incorporate grassroots approaches, robust twinning relationships, and implementation science.

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Section: Pediatric Oncology Clinical Trial Collaborative Groups By Re...mentioning

confidence: 99%

Mapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage

Major

Palese

Ermis

et al. 2022

JCO Global Oncology

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Advances in the Global Initiative for Childhood Cancer: implementation in Latin America and the Caribbean

Vásquez,

Fuentes-Alabí,

Loggetto

et al. 2023

Revista Panamericana De Salud Pública

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This report describes the status of childhood cancer control initiatives in Latin America and the Caribbean (LAC). Progress between 2017 and 2023 is measured using the outcome indicators from the Pan American Health Organization (PAHO) childhood cancer logic model aligned with the World Health Organization Global Initiative for Childhood Cancer (GICC). This report also describes the advances, barriers, and facilitators for the implementation of the GICC at the Regional level. Methods used in this report encompassed a comprehensive approach, incorporating a literature review, interviews, surveys, and a Delphi study developed by the technical team of the PAHO Non-Communicable Diseases and Mental Health Department and by the GICC LAC working group. Since 2017, there has been a substantial increase in the number of countries that have included childhood cancer in their national regulations. Currently, 21 LAC countries are involved in the GICC implementation, activities, and dialogues. However, the objectives for 2030 will only be achieved if Member States overcome the barriers to accelerating the pace of initiative implementation. There is an urgent need to increase the efforts in childhood cancer control in LAC, especially regarding the prioritization of timely detection, essential diagnostics, access to cancer treatment, palliative care, and close follow-up of children and adolescents with cancer.

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Is it Possible to Work together in Latin America? Creation of a Latin American Consortium (CLEHOP)

Cited by 2 publications

References 0 publications

Mapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage

Mapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage

Advances in the Global Initiative for Childhood Cancer: implementation in Latin America and the Caribbean

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