Is It Possible to Predict Sepsis, the Most Serious Complication in Prostate Biopsy?

Şimşir, Adnan; Kısmalı, Erkan; Mammadov, Rashad; Altıntaş, Raşit; Çal, Çağ

doi:10.1016/s0022-5347(09)60195-6

Cited by 15 publications

(27 citation statements)

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“…Transrectal prostate biopsy (TRPB) is the standard procedure in the diagnosis of prostate cancer [1,2]. Even though it is well tolerated, it is not totally riskfree, as is the case in any other invasive procedures [3].…”

Section: Introductionmentioning

confidence: 99%

Risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic flora

Eruz

Yalçı

Özden

et al. 2017

J Infect Dev Ctries

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Introduction: In this study, we aimed to identify risk factors for the development of infectious complications after prostate biopsy and to investigate the role of intestinal colonization of bacteria that are resistant to prophylactic antibiotics. Methodology: A total of 168 patients who had undergone transrectal prostate biopsy (TRPB) under ciprofloxacin and gentamycin prophylaxis were included in the study. Stool cultures and subsequent antibiotic susceptibility testing were performed in all patients before the start of antibiotic prophylaxis. Results: Of the 168 patients, 17 (10.1%) developed urinary tract infection (UTI), while 6 (3.57%) developed sepsis within seven days after biopsy. Ciprofloxacin-resistant bacterial colonization was detected in 81 (48.2%) of the patients. None of the patients with ciprofloxacinsensitive bacteria in intestinal flora developed a UTI. The colonization of intestinal ciprofloxacin-resistant bacteria increased UTI risk significantly after TRPB (p < 0.0001). Urolithiasis history, presence of permanent urinary catheterization, hospitalization history for more than 48 hours in the last year, and recent antibiotic usage significantly increased UTI risk after TRPB. Conclusions: Development of an infection was more frequent in patients with resistant bacterial colonization. We hope to guide more comprehensive studies designed to find a standard prophylactic regimen for TRPB that can be used all over the world.

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Section: Introductionmentioning

confidence: 99%

Risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic flora

Eruz

Yalçı

Özden

et al. 2017

J Infect Dev Ctries

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“…Simsir et al [11] reported a similar frequency of 3.06%. However, other studies from North America [12,13] reported lower rates of sepsis (0.6%), and an Asian study [14] reported that 0.5% of prostate biopsy cases had fever, similar to the data of our study.…”

Section: Discussionmentioning

confidence: 82%

“…Assessment of risk factors for infection and antibiotics resistance, thorough history, and physical examination was recommended [16]. Earlier studies reported that risk factors of infectionrelated complications were DM [8,11,[17][18][19], comorbidities [6], more biopsy cores [11,[20][21][22], and repeat biopsy [11,16,23]. Significant risk factors for fever after TRUS biopsy included prostate size and DM in the Rotterdam section of the ERSPC trial [8].…”

Section: Discussionmentioning

confidence: 99%

Characteristics of Patients Who Visited the Emergency Room after Prostate Biopsy: Single Center Retrospective Study

Jeong

Lee

Chung

2015

Urogenit Tract Infect

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Purpose: To educate patients and prevent biopsy-related complications, it is helpful to understand the causes for visiting the emergency room (ER).Therefore, we want to analyze the causes and factors of complications that cause patients to visit the ER after prostate biopsy. Materials and Methods:We conducted a study of in-patients who visited the ER of Pusan National University Yangsan Hospital after prostate biopsy from December 2008 to July 2015. Age, postoperative interval before visiting the ER, Charlson comorbidity index (CCI) score, symptoms in ER, prostate size, pathologic result, and number of biopsy cores were analyzed retrospectively. Results: Among all 1,694 cases of patients who had undergone prostate biopsies during a 7-year period, only 37 patients (2.2%) visited the ER. Diabetes mellitus (DM) is the most common underlying disease among patients with accompanying infection-related symptoms compared to patients with accompanying non-infection-related symptoms (p＜0.001). In univariate analysis, DM (p=0.004) and CCI score (p=0.030) were statistically significant risk factors for infection, but only DM was significant in multivariate analysis (p=0.004). Prostate size (p=0.044) was a significant risk factor for acute urinary retention (AUR) in univariate analysis, but not statistically significant in multivariate analysis. CCI score was a statistically significant risk factor for bleeding (p=0.005 [univariate], 0.035 [multivariate]). Conclusions: AUR after transrectal ultrasound-biopsy is the most common reason for visiting the ER. CCI score showed correlation with bleeding and DM showed correlation with infection. Consideration of risk factors of complications after prostate biopsy will be helpful to the patients in the treatment and prevention of complication.

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“…Furthermore, clinical staging did not include imaging examinations. Inter-examiner bias may have caused eventual misclassifications of clinical stage and of pathological examinations of surgical specimens (29).…”

Section: Discussionmentioning

confidence: 99%

External validation of a brazilian predictive nomogram for pathologic outcomes following radical prostatectomy in tertiary teaching institutions: the USP nomograms

et al. 2014

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Is It Possible to Predict Sepsis, the Most Serious Complication in Prostate Biopsy?

Cited by 15 publications

References 0 publications

Risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic flora

Risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic flora

Characteristics of Patients Who Visited the Emergency Room after Prostate Biopsy: Single Center Retrospective Study

External validation of a brazilian predictive nomogram for pathologic outcomes following radical prostatectomy in tertiary teaching institutions: the USP nomograms

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