Is it possible to identify dengue in children on the basis of Ministry of Health criteria for suspected dengue cases?

Rodrigues, Marisa B. P.; Freire, Heliane B.M.; Corrêa, Paulo Roberto Lopes; Mendonça, Marislaine Lumena de; Silva, Maria Regina I.; França, Elizabeth

doi:10.2223/jped.1341

Cited by 4 publications

(4 citation statements)

References 12 publications

(20 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was also found that almost half of patients studied had different causes of febrile illness with clinical manifestations similar to those of dengue, without significant differences. [17,21,22] As in our study, these studies found that acute respiratory infections to be the most frequent cause of UFS in several regions of the world. [23][24][25] In Cuba, acute respiratory infections are also important contributors to morbidity and hospitalizations, and are the primary reason for outpatient visits.…”

Section: Reprintsupporting

confidence: 71%

Prevalence of Febrile Syndromes in Dengue Surveillance, Havana City, 2007

Peláez

Sánchez²,

Más³

et al. 2011

MEDICC Review

View full text Add to dashboard Cite

OBJECTIVE Determine point prevalence of febrile syndromes and compare with prevalence reported by habitual clinical and seroepidemiologic dengue surveillance system in Havana City. METHODSIn October 2007, a descriptive, cross-sectional study was carried out in a representative sample, calculating prevalences of febrile syndromes and undifferentiated febrile syndromes. Chi-square analysis was used for rate comparisons.RESULTS Point prevalences of febrile syndromes and undifferentiated febrile syndromes were 352.6 and 144.2 times greater, respectively, than those reported by the habitual clinical and seroepidemiologic dengue surveillance system; these differences were statistically signifi cant (p < 0.001).CONCLUSIONS Point prevalence of febrile syndromes was far greater than prevalence reported by the habitual clinical and seroepidemiologic dengue surveillance system, an indication of underreporting.

show abstract

Section: Reprintsupporting

confidence: 71%

Prevalence of Febrile Syndromes in Dengue Surveillance, Havana City, 2007

Peláez

Sánchez²,

Más³

et al. 2011

MEDICC Review

View full text Add to dashboard Cite

show abstract

“…Although standardized diagnostic criteria 39 are widely used, the clinical diagnosis of DENV infection in Brazil remains notoriously inaccurate, [40][41][42] because several locally prevalent febrile illnesses may be misdiagnosed as dengue fever. Here we show that 1) dengue accounted for only 11 of 102 (10.8%) febrile episodes of non-malarial origin occurring in patients from rural and urban areas of eastern Acre, 2) even though a self-reported history of dengue diagnosis was a strong predictor of seroconversion during the follow-up (Table 4), only 4 of 24 subjects self-reporting a dengue fever episode during the follow-up actually seroconverted, and 3) most (6 of 10) of those with PRNT-confirmed DENV seroconversion reported no clinically diagnosed dengue fever episode during the follow-up.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for Dengue Virus Infection in Rural Amazonia: Population-based Cross-sectional Surveys

Silva‐Nunes¹,

Souza²,

Pannuti³

et al. 2008

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

A comparison of dengue virus (DENV) antibody levels in paired serum samples collected from predominantly DENV-naive residents in an agricultural settlement in Brazilian Amazonia (baseline seroprevalence, 18.3%) showed a seroconversion rate of 3.67 episodes/100 person-years at risk during 12 months of follow-up. Multivariate analysis identified male sex, poverty, and migration from extra-Amazonian states as significant predictors of baseline DENV seropositivity, whereas male sex, a history of clinical diagnosis of dengue fever, and travel to an urban area predicted subsequent seroconversion. The laboratory surveillance of acute febrile illnesses implemented at the study site and in a nearby town between 2004 and 2006 confirmed 11 DENV infections among 102 episodes studied with DENV IgM detection, reverse transcriptase-polymerase chain reaction, and virus isolation; DENV-3 was isolated. Because DENV exposure is associated with migration or travel, personal protection measures when visiting high-risk urban areas may reduce the incidence of DENV infection in this rural population.

show abstract

“…In children, dengue can be asymptomatic or polysymptomatic, which may hinder the differential diagnosis. 8 , 9 …”

Section: Introductionmentioning

confidence: 99%

“… 4 Thus, laboratory tests combined with a guided clinical examination, especially in endemic areas, are crucial to confirm a diagnosis, identify, and prevent outbreaks and provide early treatment for the severe forms of the disease and complications. 9 …”

Section: Introductionmentioning

confidence: 99%

Comparison of clinical and laboratory characteristics between children and adults with dengue

Souza

Pessanha

Mansur

et al. 2013

The Brazilian Journal of Infectious Diseases

View full text Add to dashboard Cite

Over the past several years, the epidemiological profile of dengue has been changing progressively and is currently characterized by an increase in the number of cases in children under 15 years of age. This study was aimed at comparing the clinical and laboratory features between adults and children with dengue; therefore, we performed a cross-sectional analysis of 5686 individuals with laboratory-confirmed dengue who sought treatment at a healthcare facility in Rio de Janeiro, Brazil from 2010 to 2011. A multivariate analysis indicated that myalgia (OR=2.58; CI 95%=2.08-3.18), retro-orbital pain (OR=1.36; CI 95%=1.15-1.62), nausea (OR=1.92; CI 95%=1.60-2.30), and arthralgia (OR=3.64; CI 95%=2.72-4.89) were the most frequent clinical symptoms in adults, whereas vomiting (OR=0.52; CI 95%=0.43-0.61) and skin rash (OR=0.46; CI 95%=0.25-0.85) were the most prevalent symptoms in children. Adults exhibited a higher hemoconcentration (OR=3.04; CI 95%=2.53-3.65), thrombocytopenia (OR=2.17; CI 95%=1.80-2.60), increased erythrocyte sedimentation rate (OR=1.81; CI 95%=1.53-2.14), and increased ALT (OR=3.13; CI 95%=2.44-4.02) than did children. In addition, adults exhibited a higher frequency of the severe forms of the disease (OR=1.74; CI 95%=1.12-2.72) and hospitalization (OR=2.21; CI 95%=1.59-3.06) relative to children. Based on these results, this study demonstrated significant differences in the clinical and laboratory presentations and disease severity between adults and children affected by dengue.

show abstract

Is it possible to identify dengue in children on the basis of Ministry of Health criteria for suspected dengue cases?

Cited by 4 publications

References 12 publications

Prevalence of Febrile Syndromes in Dengue Surveillance, Havana City, 2007

Prevalence of Febrile Syndromes in Dengue Surveillance, Havana City, 2007

Risk Factors for Dengue Virus Infection in Rural Amazonia: Population-based Cross-sectional Surveys

Comparison of clinical and laboratory characteristics between children and adults with dengue

Contact Info

Product

Resources

About