Is it possible to develop a vaccine against depression based on microRNA?

Abstract

It is difficult to create vaccinations to prevent mental diseases like depression because of their complex underlying mechanisms. In order to create an effective vaccine, the underlying causes of these diseases must be understood. In addition, it has been observed that microRNAs are crucial regulators of various cell functions, including proliferation, growth, differentiation, neoplastic transformation, and tissue regeneration. Their importance goes beyond posttranscriptional control of gene expression. In light of this, the study recommends employing microRNA in the production of live-attenuated vaccines to produce strong, long-lasting immunity against mental diseases.