Is infection a major risk factor for preeclampsia?

Herrera, Julián A.; Chaudhuri, Gautam; López‐Jaramillo, Patricio

doi:10.1054/mehy.2001.1378

Cited by 84 publications

(76 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These include direct effects of the infectious agents on the arterial walls, including endothelial injury or dysfunction, acute atherosis, and local inflammation that might cause relative uteroplacental ischemia (von Dadelszen & Magee, 2002). Furthermore, some authors have hypothesized that the infection might be involved in both the initiation of the pre-eclampsia process (by increasing the risk of acute uteroplacental atherosis) and/or its potentiation (by amplifying the maternal systemic inflammatory response) (Herrera et al, 2001). Nevertheless, these hypotheses are issued from animal data and some other authors argue that the association between UTIs and preeclampsia may not be real and may be due to confounding.…”

Section: ) a L T H O U G H B A C T E R E M I A I S D E T E C T E mentioning

confidence: 99%

Urinary Tract Infections During Pregnancy

Berard¹,

Santos²,

Ferreira³

et al. 2011

Urinary Tract Infections

View full text Add to dashboard Cite

Section: ) a L T H O U G H B A C T E R E M I A I S D E T E C T E mentioning

confidence: 99%

Urinary Tract Infections During Pregnancy

Berard¹,

Santos²,

Ferreira³

et al. 2011

Urinary Tract Infections

View full text Add to dashboard Cite

“…28 The higher incidence of preeclampsia in group I women can be attributed to increased maternal cytokines found in ASB may reflect vascular endothelial function which in turn leads to preeclampsia. 29 The incidence of anaemia was found to be high (14.7%) in group I pregnant women as compared to group II (4.5%). The results were in agreement with many previous studies where the higher incidence of anaemia has been reported to be associated with ASB.…”

Section: Discussionmentioning

confidence: 80%

Prevalence of asymptomatic bacteriuria among antenatal women and its effects on maternal and perinatal outcome in northern Andhra Pradesh population

et al. 2018

View full text Add to dashboard Cite

INTRODUCTIONAsymptomatic bacteriuria (ASB) is a condition in which urine culture reveals a significant growth of pathogenic bacteria i.e. greater than 105 bacteria/mL without the presence of symptoms related to urinary tract infection (UTI).1 The pregnant women are more commonly affected than non-pregnant women due to various morphological, physiological changes and urinary stasis that occur during pregnancy due to the effect of progesterone. 2 The prevalence of ASB in pregnant women varies from 4% to 23.9% globally and the higher prevalence is attributed to lack of personal and environmental hygiene, socio-economic status, parity and ABSTRACT Background: The pregnant women are more commonly affected with asymptomatic bacteriuria (ASB) than nonpregnant women and its progression could lead to adverse maternal and perinatal outcomes. The study was designed with an aim to know the prevalence of ASB and its effects on maternal and perinatal outcome. Methods: In this prospective study, 300 antenatal women attending Anil Neerukonda Hospital were screened for ASB. Urine culture was performed using standardized Kirby-Bauer disc diffusion method on blood agar, Mac Conkey's agar for antibiotic sensitivity testing. The screened antenatal women were divided into two subgroups viz. asymptomatic bacteriuria positive (Group I) and asymptomatic bacteriuria negative (Group II) depending on the culture study and were followed till delivery for maternal and perinatal outcomes. Results: The prevalence of ASB was 11.33%. Out of 34 cases of ASB positive, 8 cases (23.5%) were delivered with birth weight <2500 grams as compared to 11 cases (4.1%) in unexposed cases (RR 5.68, 95% CI; 2.46-13.15; p<0.05). Preterm low birth was noticed in 5 (14.7%) cases of ASB positive pregnant women with compared to unexposed cases (RR 1.5, 95% CI; 0.61-3.65, p=0.36). Regarding maternal outcomes, premature labour was observed in 8 cases (23.5%) of ASB exposed women whereas 22 (8.3%) in non-exposed cases (RR 2.84, 95% CI; p=0.004). A significant number of women have developed hypertension (17.6%) and preeclampsia (8.8%) in ASB positive cases as compared to ASB negative cases (4.9% and 2.3% respectively). Conclusions: The prevalence of ASB was 11.33% in the present study. As one third of the cases were identified in early and late trimesters, regular and trimester wise screening need to be incorporated in routine antenatal screening for safe motherhood and new born health.

show abstract

“…A causa de la fuerte correlación entre las infecciones urinarias y periodontales y la preeclampsia 133 , es de importancia capital buscar y tratar la bacteriuria, y las infecciones urinarias, vaginales y periodontales en las mujeres embarazadas. Si no hay una respuesta terapéutica adecuada, las decisiones dependen de la edad gestacional: si es >36 semanas se debe interrumpir el embarazo.…”

Section: Detección De Infecciones Subclínicasunclassified