IsMycoplasma genitaliumin Women the “New Chlamydia?” A Community‐Based Prospective Cohort Study

Abstract

M. genitalium infection is unlikely to be a major risk factor for clinical pelvic inflammatory disease in this population.

Mycoplasma genitalium: from Chrysalis to Multicolored Butterfly

“…However, unlike M. hominis, which is very strongly, if not causally, associated with bacterial vaginosis (BV) (173) in which inflammatory cells are absent, the association of M. genitalium with BV is controversial. In three studies (114,119,137), there was no evidence that M. genitalium played any part in BV, while in a fourth study (158), the presence of M. genitalium in women was independently associated with BV, being more common in women with BV than in those without the condition. Clearly, this does not necessarily mean that there is a causal relationship, but the issue needs to be resolved.…”

“…With regard to screening, the cost-effectiveness of such a procedure has to be considered, as the prevalence of M. genitalium in the general population is relatively low. Prevalence figures of 0.7% to no more than 3.3% have been recorded (3,64,138,158,159), generally 4 to 5 times less than those for C. trachomatis, and probably do not justify widespread screening programs. However, the selective screening of individuals who can be considered particularly vulnerable on the basis of certain risk factors (for example, young age, early sexual debut, more than one sexual partner, change of sexual partner, and presenting with symptoms) may be a worthwhile approach.…”

“…PID comprises endometritis and/or salpingitis, and studies of these anatomical sites of infection are discussed below. Laparoscopy is not often undertaken, and two studies (180,181) in which M. genitalium was associated with PID were based on clinical examination alone and did not make the finer anatomical distinction; in a third longitudinal study (158), there was only a trend in the direction of PID being associated with M. genitalium. In a study of women presenting for termination of pregnancy in New Zealand (119), there was a high rate of M. genitalium infection (9%) based on self-taken vaginal swabs.…”

The Ballseye programme: a mixed-methods programme of research in traditional sexual health and alternative community settings to improve the sexual health of men in the UK

“…Currently, men accessing health services are recommended to undergo urethral smear microscopy only if they have symptoms of urethritis 63 (although some clinics continue the practice). This means that asymptomatic NCNGU ceases to be a diagnosable and treated condition.…”

“…These parameters were varied in combination across their prior ranges and the resulting model run compared with the target values for annual diagnoses in GUM clinics in men (10-46% of NCNGU diagnoses), and the prevalence in women derived from the study by Oakeshott et al 63 Candidate parameter sets were accepted if both the criteria were met.…”