Is Helicobacter Pylori a Possible Etiopathogenic Factor in Chronic Tonsillitis?

Abstract

Anahtar KelimelerHelikobakter Pilori; Tonsillektomi; Tonsil; Tonsillit; Giemsa Abstract Aim: Helicobacter pylori is the major gastric pathogen which has an important role in the etiopathogenesis of chronic gastritis. We investigated the presence of Helicobacter pylori as an extragastric reservoir in the tonsillectomy specimens to display if it is an etiologic factor in the development of chronic tonsilitis. Material and Method: In the current study, 100 cases with chronic tonsilitis were examined in bilateral tonsillectomy specimens. The colonization of the microorganism have been evaluated with hematoxylineosin and giemsa stains under the light microscope.Results: Helicobacter pylori has been detected in 33 cases (33%) on one side of the bilateral tonsillectomy specimens while it has been seen in 15 cases (15%) on both sides which demonstrated positivity in 48 cases (48%) in total. No colonization has been observed in the remaining 52 cases (52%). Discussion: Due to the considerable positivity in our study, the histopathologic evaluation of tonsillary Helicobacter pylori colonization may be instrumental in the etiologic association with chronic tonsillitis.

Overview of Helicobacter pylori Detection Using Rapid Urease Test and Giemsa Modification Staining in Chronic Tonsillitis Patients

“…The results obtained 76% were positive H. pylori in patients with chronic tonsillitis. This is convenient with the results of the Ozgun et al report of 100 cases studied, where 48 cases (48%) showed a depiction of H. pylori from a tonsillar mucosal surface specimen by Giemsa examination [6]. The combination of two or three methods can confirm true positive results and then can be used as a "gold standard" in the methodology survey for the detection of H. pylori [18].…”

“…Several studies have implicated that tonsils can be a potential colonization site for H. pylori. Ozgun et al [6] reported that out of 100 patients who underwent tonsillectomy, 48 (48%) were H. pylori positive and 52 (52%) were negative. Lin et al [7] reported that of 94 patients who were treated for tonsillitis, 33 (35%) were positive for H. pylori and 61 (65%) were negative.…”

Prevalence of H pylorii In The Tonsillar Tissue of The Children With Giemsa Stain.

“…Histokimyasal analiz (Modifiye Giemsa yöntemi) ile Hp arayan Özgün ve ark. (20) 100 tonsillektomi spesmeninden 48'inde (%48) pozitif sonuç bulmuşlardır. Sonuç olarak, kronik tonsillit için Hp'nin etiyolojik bir ajan olabileceğini ancak oral mukozanın kompleksliği dolayısıyla tezlerinin diğer testler ile doğrulanması gerektiğini savunmuşlardır.…”