Is Fournier’s Gangrene Severity Index Useful for Predicting Outcome of Fournier’s Gangrene?

Lin, Eugene C.; Yang, Stone; Chiu, Allen W.; Chow, Yung Chiong; Chen, Marcelo; Lin, Wea‐Lung; Chang, Hong-Yeh; Hsu, Jong Ming; Lo, King Yik; Hsu, Hsi Hsien

doi:10.1159/000087164

Cited by 41 publications

(30 citation statements)

References 20 publications

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“…Unlike our study, Tuncel et al [2] found significant differences between survivors and nonsurvivors in albumin and ALP levels. Similarly, Lin et al [20] found that serum albumin levels between survivors and nonsurvivors at admission were significantly different.…”

Section: Discussionmentioning

confidence: 94%

Epidemiological Characteristics of Fournier’s Gangrene: A Report of 71 Patients

Aridogan

İzol²,

Abat³

et al. 2012

Urol Int

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Introduction: To identify the predisposing factors, etiological and clinical characteristics as well as the Fournier’s gangrene (FG) severity index (FGSI) in the outcomes of patients with FG. Materials and Methods: The data from 71 patients diagnosed with FG in a period of 17 years were retrospectively reviewed for the age of the patient, their history, predisposing factors, etiology, prodromal symptoms, FGSI, culture results, hospitalization period, surgical interventions, responses to the therapy and complications. Results: All of the patients were Caucasian males, and the mean age was 61.3 (range 36–92) years. The mean duration from the onset of symptoms to surgery was 7.5 days. The mean hospitalization time was 27.4 days and the most common etiological factor for FG was a perineal abscess. The overall mortality rate was 29.6%. The relationship between the number of predisposing factors and mortality rates in patients with FG was the most statistically significant parameter (p = 0.001). Conclusions: Multiple predisposing factors predict a poor prognosis and correlate significantly with mortality. Extension of the disease and the FGSI score were not predictive of outcome. The most essential intervention for stopping the rapidly progressing infectious process of FG consists of early recognition of the disease, proper management of the predisposing factors and aggressive surgical debridement. Such an intervention can improve clinical outcomes.

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Section: Discussionmentioning

confidence: 94%

Epidemiological Characteristics of Fournier’s Gangrene: A Report of 71 Patients

Aridogan

İzol²,

Abat³

et al. 2012

Urol Int

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show abstract

“…Lin E, and others suggested that a FGSI cutoff of 9 was an excellent predictor of outcome of cases. 24 However, diagnosis, treatment and the arrest of the gangrene at an early stage markedly improve outcome. A study conducted by Tuncel et al on 20 Fournier's gangrene patients concluded that FGSI did not predict the disease severity and the patient survival.…”

Section: Discussionmentioning

confidence: 99%

Fournier's gangrene: a prospective study of 57 patients with special reference to validity of Fournier's gangrene severity index in predicting the outcome and mortality

2016

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“…This index was based on data gathered from only 30 patients presenting to a referral center over a 15-year period. Other investigators reported variable accuracy using the Fournier's Gangrene Severity Index to predict mortality [13,14,15,16,17,18]. …”

Section: Introductionmentioning

confidence: 99%

Fournier's Gangrene: Epidemiology and Outcomes in the General US Population

2016

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Purpose: Case series reported 20-40% mortality rates for patients with Fournier's gangrene with some series as high as 88%. This literature comes almost exclusively from referral centers. Materials and Methods: We identified and analyzed inpatients with Fournier's gangrene who had a surgical debridement or died in the US State Inpatient Databases. Results: One thousand six hundred and forty one males and 39 females with Fournier's gangrene represented <0.02% of hospital admissions. Overall, the incidence was 1.6 cases per 100,000 males and case fatality was 7.5%. Sixty six percent of hospitals cared for no cases per year, 17% cared for 1 case per year, 10% cared for 2 cases per year, 4% cared for 3 cases per year, 1% cared for 4 cases per year, and only 1% cared for ≥5 cases per year. Teaching hospitals had higher mortality (adjusted OR 1.9) due primarily to more acutely ill patients. Hospitals treating more than 1 Fournier's gangrene case per year had an adjusted 42-84% lower mortality (p < 0.0001). Conclusions: Most hospitals rarely care for Fournier's gangrene patients. The population-based mortality rate (7.5%) was substantially lower than the case series from tertiary care centers. Hospitals that treated more number of Fournier's gangrene patients had lower mortality rates, thereby supporting the rationale that regionalized care worked well for patients with this rare disease.

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Is Fournier’s Gangrene Severity Index Useful for Predicting Outcome of Fournier’s Gangrene?

Cited by 41 publications

References 20 publications

Epidemiological Characteristics of Fournier’s Gangrene: A Report of 71 Patients

Epidemiological Characteristics of Fournier’s Gangrene: A Report of 71 Patients

Fournier's gangrene: a prospective study of 57 patients with special reference to validity of Fournier's gangrene severity index in predicting the outcome and mortality

Fournier's Gangrene: Epidemiology and Outcomes in the General US Population

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