Is ESR Important for Predicting Post-ERCP Pancreatitis?

Alizadeh, Amir Houshang Mohammad; Afzali, Esmaeil Shamsi; Behzad, Catherine; Mousavi, Mirhadi; Mirsattari, Dariush; Doagoo, Siavash Zafar; Zali, Mohammad Reza

doi:10.4137/cgast.s18938

Cited by 3 publications

(3 citation statements)

References 31 publications

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“…Among markers which were proven to be associated with PEP by a small observational series were: trypsinogen, trypsinogen activation peptide, C-reactive protein (CRP), serum elastase-1, erythrocyte sedimentation rate (ESR), chemerin, and various interleukins such as IL-6 and IL-10. 11,[33][34][35][36][37][38] Yet, the distinction between hyperamylasemia with transient abdominal discomfort (TAD) due to post-procedural intestinal distension and PEP remains difficult to establish during the first 24 h after the procedure.…”

Section: Definition Of Post-ercp Pancreatitismentioning

confidence: 99%

Post-ERCP pancreatitis: Pathophysiology, early identification and risk stratification

Tryliskyy¹,

Bryce²

2018

Adv Clin Exp Med

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Acute pancreatitis is the most common and feared complication of endoscopic retrograde cholangiopancreatography (ERCP). The aim of the study was to review the current knowledge on the nomenclature, etiology, pathophysiology, clinical presentation, diagnostic workup, and risk stratification of post-ERCP pancreatitis (PEP). A structured search in PubMed and Scopus databases was performed using search terms related to the subject of diagnosis, pathophysiology, risk stratification of post-ERCP pancreatitis, including full text articles and abstracts in the English language. Several causes, operating both at a local and systemic level, might play an important role in the pathogenesis of PEP. Different patient-related risk factors can help predict post-ERCP pancreatitis; diagnosis depends on clinical presentation, imaging and laboratory investigations. As an outpatient procedure, post-ERCP pancreatitis may be safe in a selected group of low-risk patients. Further investigation of the etio-pathogenesis of post-ERCP pancreatitis is required in order to improve diagnosis and treatment. Early identification and severity stratification of post-ERCP pancreatitis greatly affects the patient's outcome. There is still controversy concerning the risk factors related to PEP. More studies are needed to clarify early and definite diagnosis, risk and severity stratification, as well as treatment of post-ERCP pancreatitis.

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Section: Definition Of Post-ercp Pancreatitismentioning

confidence: 99%

Post-ERCP pancreatitis: Pathophysiology, early identification and risk stratification

Tryliskyy¹,

Bryce²

2018

Adv Clin Exp Med

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“…Other alternative biochemical markers for PEP diagnosis have been suggested by small observational series. Among the markers that were proven to be associated with PEP were trypsinogen, trypsinogen activation peptide, C-reactive protein, serum elastase-1, erythrocyte sedimentation rate, chemerin, and various interleukins (ILs) such as IL-6 and IL-10 [31][32][33][34][35][36].…”

Section: Clinical Presentation and Diagnosismentioning

confidence: 99%

Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis: What We Already Know

Obeidat¹,

Mahfouz²,

G³

et al. 2022

Cureus

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Acute pancreatitis is the most common serious complication of endoscopic retrograde cholangiopancreatography (ERCP) resulting in significant morbidity and occasional mortality. Post-ERCP pancreatitis (PEP) has been recognized since ERCP was first performed, and many studies have shown a consistent risk that must be balanced against the many benefits of this procedure. This review will discuss the pathogenesis, epidemiology, potential risk factors, and clinical presentation of PEP. Moreover, it will discuss in detail the most recent updates of PEP prevention and management.

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“…The most important complications of this procedure could be infectious, hemorrhage, perforation and post-ERCP pancreatitis (PEP). 2,3 One of the most common complications is acute pancreatitis that imposes major problems such as morbidity, occasional death and increasing of health care expenditures to the patients. 4,5 The occurrence of post-ERCP pancreatitis ranges in different studies depending on patient selection, reported from 1-15.7%, however this amount at high-risk patients reaches to 30%.…”

Section: Introductionmentioning

confidence: 99%

The comparison between combination of pancreatic stent and nsaid with nsaid alone in preventing post ERCP pancreatitis

Heidarnezhad¹,

Mohammad²

2018

GHOA

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ERCP as a diagnostic and therapeutic tool for biliary tract and pancreatic diseases is associated with many complications such as Pancreatitis, bleeding, perforation, and cardiovascular consequences. A recent survey showed that the use of non-steroid antiinflammatory drugs before ERCP could reduce risk of pancreatitis after ERCP. In order to assess this hypothesis in the patients admitted to Taleghani hospital, Tehran, Iran, with CBD stone, we designed the current study. After randomized selection and division of the patients to different groups; the patient's candidate for pancreatic duct stent (PD stent) and Indomethacin-supplement procedure and the patients under Indomethacin-supplement process alone. After evaluating different variabilities as sex, age, Post ERCP Pancreatitis (PEP) with use of PD stent, PEP with use of indomethacin-supplement and PD stent, medications, type of disease, laboratory test such as CBC, AST, ALT and bilirubin test, ERCP was conducted by one expert specialist. Blinding of the staff and analysis department was conducted as well. Data analysis showed that <10 minutes of cannulation could decrease the incidence of PEP in our study (P-value<0.05), while other variables did not manifested any correlation with the incidence of PEP. In conclusion, we showed the evidence that different interventional elements or patient associated risk factors had no significantly effect on PEP incidence. However, deep cannulation time as the important factor of procedure could alter the rate of PEP.

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Is ESR Important for Predicting Post-ERCP Pancreatitis?

Cited by 3 publications

References 31 publications

Post-ERCP pancreatitis: Pathophysiology, early identification and risk stratification

Post-ERCP pancreatitis: Pathophysiology, early identification and risk stratification

Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis: What We Already Know

The comparison between combination of pancreatic stent and nsaid with nsaid alone in preventing post ERCP pancreatitis

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