Is e-cigarette use in non-smoking young adults associated with later smoking? A systematic review and meta-analysis

Khouja, Jasmine N; Suddell, Steph; Peters, Sarah Elizabeth; Taylor, Amy E; Munafò, Marcus R.

doi:10.1101/19007005

Cited by 38 publications

(53 citation statements)

References 37 publications

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“…In the adolescent brain, nicotine exposure is associated with cognitive deficits, impairment in memory and in executive function [ 10 ]. Evidence that e-cigarettes lead to later tobacco use, a process known as the “gateway” effect, continues to mount [ 11 ]. Emerging literature suggests that the long term adverse effects include myocardial infarction [ 12 ], stroke [ 13 ], respiratory disease [ 14 ], and potential carcinogenic effects [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

E-Cigarette-Only and Dual Use among Adolescents in Ireland: Emerging Behaviours with Different Risk Profiles

Bowe

Doyle

Stanistreet

et al. 2021

IJERPH

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E-cigarette-only use and dual-use are emerging behaviours among adolescent nicotine product users which have not yet been sufficiently explored. This study examines the prevalence of, and the factors associated with, nicotine product use in adolescence. The study is a cross-sectional analysis of the 2018 Planet Youth survey completed by 15–16 year olds in the West of Ireland in 2018. The outcome of interest was current nicotine product use, defined as use at least once in the past 30 days. A main effects multinomial logistic regression model was used to examine the association between potential risk and protective factors and nicotine product use. Among 4422 adolescents 22.1% were current nicotine product users, consisting of 5.1% e-cigarette only users, 7.7% conventional cigarette only users, and 9.3% dual-users. For risk factors, the odds of association were weaker for e-cigarette only use compared to conventional cigarette and dual use. Participating in team sport four times/week or more significantly reduced the odds of conventional cigarette and dual use but had no association with e-cigarette only use (Cig: adjusted odds ratio (AOR) 0.63, 95% confidence interval (CI) 0.44–0.90; Dual-use: AOR 0.63, 95% CI 0.43–0.93). Similarly, having higher value for conventional social norms reduced the odds of conventional cigarette and dual use but not e-cigarette only use. This is the first study to show, among a generalisable sample, that dual-use is the most prevalent behaviour among adolescent nicotine product users in Ireland. Risk factor profiles differ across categories of use and prevention initiatives must be cognisant of this.

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Section: Introductionmentioning

confidence: 99%

E-Cigarette-Only and Dual Use among Adolescents in Ireland: Emerging Behaviours with Different Risk Profiles

Bowe

Doyle

Stanistreet

et al. 2021

IJERPH

View full text Add to dashboard Cite

show abstract

“…6 There is also an increasing body of literature indicating e-cigarette use is associated with future conventional cigarette smoking. 1 , 7 - 11 However, the evidence is limited to self-report measures. 10 Given the addictiveness and harmful effects of e-cigarettes, it is crucial to identify predictors of e-cigarette initiation among youth and young adults to prevent them from initiating.…”

Section: Introductionmentioning

confidence: 99%

Predictors of E-Cigarette Initiation: Findings From the Youth and Young Adult Panel Study

2020

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Objectives: Although previous studies have identified reasons why youth try e-cigarettes, longitudinal research is needed to identify predictors of e-cigarette initiation. This study assesses predictors of e-cigarette initiation among youth and young adults in the 2018-2019 Youth and Young Adult Panel Study. Methods: This study examined the proportion of Canadian participants aged 16 to 25 (n = 137) reporting never use of e-cigarettes at baseline in 2018. Individuals were categorized as not initiated and initiated at 12-month follow-up. We examined demographic characteristics, substance use, health status, social influences and perception by initiation category. Adjusted odds ratios (AORs) were calculated using logistic regression models and multivariable logistic regression model. Results: Among the 137 never e-cigarette users at baseline, 59% remained never users while 41% initiated use of e-cigarettes during the 12-month follow-up. The results of multivariable logistic regression analysis showed that regularly seeing anyone use e-cigarettes (AOR: 4.11; 95% CI: 1.04, 16.31) and seeing anyone use e-cigarettes very often or always at baseline (AOR: 4.54; 95% CI: 1.21, 17.01) is associated with initiating e-cigarette use among youth and young adults. Conclusion: The results revealed social influences to be the most important predictors of initiation among youth and young adults. Interventions to prevent youth and young adults from initiating e-cigarette use should expand from only focusing on peer use to reducing use in public space such as parks and recreational facilities.

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“…Among 12th-grade students, the prevalence of past-30-day (P30D) cigarette smoking decreased steadily from 28.3% in 1996 to 7.5% in 2020 [ 2 , 3 ]. However, e-cigarettes are becoming increasingly popular among adolescents, including those who are not susceptible to smoking cigarettes [ 4 , 5 , 6 ]. In 2020, 19.6% of high school students and 4.7% of middle school students reported using e-cigarettes in the past 30 days [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Sex Difference in the Association between Electronic Cigarette Use and Subsequent Cigarette Smoking among U.S. Adolescents: Findings from the PATH Study Waves 1–4

Duan

Wang

Huang

2021

IJERPH

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E-cigarettes are the most-used tobacco products among U.S. adolescents. Emerging evidence suggests that adolescents using e-cigarettes are at elevated risk for initiating cigarette smoking. However, whether this risk may differ by sex remains unknown. This study analyzed data from Wave 1 to 4 of the Population Assessment of Tobacco and Health (PATH) Study, a nationally representative longitudinal survey. Generalized estimation equations (GEE) were performed to estimate the associations between baseline e-cigarette use and subsequent cigarette smoking, controlling for sociodemographic characteristics, mental health conditions, and other tobacco use. Effect modifications by sex were examined. Multivariate analyses showed that, among baseline never cigarette smokers, past-30-day e-cigarette use at baseline waves was significantly associated with past-30-day cigarette smoking at follow-up waves (aOR = 3.90, 95% CI: 2.51–6.08). This association was significantly stronger for boys (aOR = 6.17, 95% CI: 2.43–15.68) than for girls (aOR = 1.10, 95% CI: 0.14–8.33). Additionally, using other tobacco products, older age, and having severe externalizing mental health problems at baseline were significantly associated with an increased likelihood of cigarette smoking at follow-up. The prospective association between e-cigarette use and cigarette smoking differs by sex among U.S. adolescents. Sex-specific tobacco control interventions may be warranted to curb the youth tobacco use epidemic.

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Is e-cigarette use in non-smoking young adults associated with later smoking? A systematic review and meta-analysis

Cited by 38 publications

References 37 publications

E-Cigarette-Only and Dual Use among Adolescents in Ireland: Emerging Behaviours with Different Risk Profiles

E-Cigarette-Only and Dual Use among Adolescents in Ireland: Emerging Behaviours with Different Risk Profiles

Predictors of E-Cigarette Initiation: Findings From the Youth and Young Adult Panel Study

Sex Difference in the Association between Electronic Cigarette Use and Subsequent Cigarette Smoking among U.S. Adolescents: Findings from the PATH Study Waves 1–4

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