Is DVT Prophylaxis Overemphasized? A Randomized Prospective Study

Kosir, Mary A.; Kozol, Robert A.; Perales, Anthony; McGee, Karen; Beleski, Karen; Lange, P; Dahn, Michael S.

doi:10.1006/jsre.1996.0045

Cited by 17 publications

(22 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The majority of trials assessing compression methods were conducted in a surgical setting: 14 were orthopaedic, 24,33,34,36,40,48,49,[51][52][53]59,60,63,64 16 general, 23,25,26,28,29,32,[37][38][39]41,42,44,50,54,61,62 six neurosurgical or after spinal surgery, 31,43,[55][56][57][58] three gynaecological 30,45,46 and one mixed surgical, 47 with only two trials 27,35 conducted among 257 medical patients at high risk of venous thromboembolism. After subdividing these trials into those assessing monotherapy and those assessing adjunctive therapy, the specific type of surgical or medical setting did not appear to influence the effectiveness of mechanical compression [heterogeneity 2 for monotherapy (on 5 df) = 4.6; p > 0.1, and heterogeneity 2 for adjunctive therapy (on 2 df) = 3.7; p > 0.1, not significant (NS); Figure 2].…”

Section: Description Of Trialsmentioning

confidence: 99%

“…In 19 trials [40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58] among 2255 patients assessing IPC as monotherapy, IPC produced a highly significant 66% (7) reduction in DVT [112/1108 (10.1%) IPC vs 268/1147 (23.4%) control, 2p < 0.00001; Figure 5a]. There was marginal evidence of heterogeneity of effect among these trials ( 2 on 16 df = 28.4; p = 0.03), but this was generated chiefly by one trial.…”

Section: Intermittent Pneumatic Compressionmentioning

confidence: 99%

See 1 more Smart Citation

Towards evidence-based guidelines for the prevention of venous thromboembolism: systematic reviews of mechanical methods, oral anticoagulation, dextran and regional anaesthesia as thromboprophylaxis

Roderick¹,

Ferris²,

Wilson³

et al. 2005

Health Technol Assess

266

151

View full text Add to dashboard Cite

Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. NHS libraries can subscribe free of charge. Public libraries can subscribe at a very reduced cost of £100 for each volume (normally comprising 30-40 titles). The commercial subscription rate is £300 per volume. Please see our website for details. Subscriptions can only be purchased for the current or forthcoming volume. Contact details are as follows: Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to Direct Mail Works Ltd and drawn on a bank with a UK address. Paying by credit cardThe following cards are accepted by phone, fax, post or via the website ordering pages: Delta, Eurocard, Mastercard, Solo, Switch and Visa. We advise against sending credit card details in a plain email. Paying by official purchase orderYou can post or fax these, but they must be from public bodies (i.e. NHS or universities) within the UK. We cannot at present accept purchase orders from commercial companies or from outside the UK. How do I get a copy of HTA on CD?Please use the form on the HTA website (www.hta.ac.uk/htacd.htm). Or contact Direct Mail Works (see contact details above) by email, post, fax or phone. HTA on CD is currently free of charge worldwide.The website also provides information about the HTA Programme and lists the membership of the various committees. HTATowards evidence-based guidelines for the prevention of venous thromboembolism: systematic reviews of mechanical methods, oral anticoagulation, dextran and regional anaesthesia as thromboprophylaxis NHS R&D HTA ProgrammeT he research findings from the NHS R&D Health Technology Assessment (HTA) Programme directly influence key decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC) who rely on HTA outputs to help raise standards of care. HTA findings also help to improve the quality of the service in the NHS indirectly in that they form a key component of the 'National Knowledge Service' that is being developed to improve the evidence of clinical practice throughout the NHS.The HTA Programme was set up in 1993. Its role is to ensure that high-quality research information on the costs, effectiveness and broader impact of health technologies is produced in the most efficient way for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined to include all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care, rather than settings of car...

show abstract

Section: Description Of Trialsmentioning

confidence: 99%

Section: Intermittent Pneumatic Compressionmentioning

confidence: 99%

Towards evidence-based guidelines for the prevention of venous thromboembolism: systematic reviews of mechanical methods, oral anticoagulation, dextran and regional anaesthesia as thromboprophylaxis

Roderick¹,

Ferris²,

Wilson³

et al. 2005

Health Technol Assess

266

151

View full text Add to dashboard Cite

show abstract

“…The electronic searches and the hand-search revealed 558 studies. Of these 19 fullfilled the criteria for inclusion for analysis [10,[13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30]. In 66 occasions primary authors and ⁄ or sponsoring pharmaceutical companies were contacted in order to obtain the colorectal data.…”

Section: Description Of Studiesmentioning

confidence: 99%

Systematic review of thromboprophylaxis in colorectal surgery – an update

2005

View full text Add to dashboard Cite

show abstract

“…The evidence for PCDs in general and abdominal surgery is inconclusive but is convincing in orthopaedic surgery. [41][42][43][44][45][46] Our use of PCDs was 53%, while all three forms of prophylaxis were used together in only 45% of patients. Hence, the use of PCDs may not be as beneficial, since we have shown that our high overall compliance with in-hospital thromboprophylaxis (especially UH/LMWH and GCS) is associated with a low incidence of VTE, including postdischarge VTE.…”

Section: Discussionmentioning

confidence: 99%