Is Corticosteroid Therapy Effective for Sudden-Onset Sensorineural Hearing Loss at Lower Frequencies?

Tabuchi, Keisaku; Hiraumi, Harukazu; Hirose, Tomoko

doi:10.1001/archotol.128.4.365

Cited by 24 publications

(19 citation statements)

References 7 publications

(15 reference statements)

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“…This resulted in about one quarter of our cases being probable cases. Previously, the peak age of ALHL onset was reported to be in the late 40s to 50s [1,2,4,7]. In our study, the mean age at onset was 47.3 years; however, the mean age of patients with definite ALHL was 40.1 years and that of patients with probable ALHL was 66.6 years.…”

Section: Discussioncontrasting

confidence: 59%

“…Pure-tone audiometry shows an increased hearing threshold limited to the low-frequency range. Previous reports about ALHL [1,2,3] have used criteria proposed in 2000 by the Acute Profound Deafness Research Committee of the Ministry of Health, Labor, and Welfare of Japan (APDRC). These criteria include normal hearing level for high tones to exclude patients with other etiologies.…”

Section: Introductionmentioning

confidence: 99%

“…ALHL is considered to be a mild illness because it tends to resolve spontaneously [2,4]. Indeed, most patients recover within several days; however, for some patients the hearing loss is intractable.…”

Section: Introductionmentioning

confidence: 99%

“…Thus, diuretics (such as isosorbide), steroids, or a combination of these drugs is used to treat ALHL. However, previous reports have shown conflicting results on the effectiveness of diuretics and steroids [2,3,10], and no consensus has been reached on the best therapeutic strategy for ALHL.…”

Section: Introductionmentioning

confidence: 99%

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Trial of Chinese Medicine Wu-Ling-San for Acute Low-Tone Hearing Loss

Okada¹,

Ishimoto²,

Fujimaki³

et al. 2012

ORL

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Purpose: We used new criteria to elucidate the demographics of acute low-tone sensorineural hearing loss (ALHL) and tested the Chinese medicine Wu-Ling-San as a treatment for ALHL. Procedures: We reviewed the medical records of patients with ALHL seen at the outpatient clinic of the Social Insurance Central General Hospital in Tokyo from April 2006 through August 2011. Patients were treated with an oral steroid, a diuretic, or Wu-Ling-San; alone or in combination. Results: We identified 130 definite and 48 probable ALHL cases. The mean age and male-to-female ratio in probable cases were significantly higher than those in definite cases (p < 0.05). The steroid-Wu-Ling-San combination was significantly more effective (100% recovery) than the diuretic alone (59%), Wu-Ling-San alone (62%), or the steroid-diuretic combination (60%, p < 0.05). Conclusions: ALHL can develop in older patients more frequently than we expected. The steroid-Wu-Ling-San combination is a possible new treatment for ALHL.

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Section: Discussioncontrasting

confidence: 59%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Trial of Chinese Medicine Wu-Ling-San for Acute Low-Tone Hearing Loss

Okada¹,

Ishimoto²,

Fujimaki³

et al. 2012

ORL

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“…Variables which may worsen the prognosis include increasing age of the patient, number of days before presentation, a more severe initial mean hearing loss and the presence of vertigo. 21,22 A better prognosis may be associated with early hearing improvement. 23 and prompt administration of corticosteroids.…”

Section: Discussionmentioning

confidence: 99%

Sudden Onset Sensorineural Hearing Loss: Management Protocol

Dash¹,

Samantray²,

Biswal³

2016

jemds

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AIMSTo study the efficacy of transcutaneous nitroglycerin and pulse steroid injection in patients with sudden hearing loss. MATERIAL AND METHODThis was a prospective study conducted in the Department of ENT, KIMS, Bhubaneswar; 31 patients who fit to inclusion criteria included in this study. RESULTSOut of 31 patients of sudden onset sensorineural hearing loss, 18 (58.06%) patients had threshold closer to 30 dB.

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Assessment of Spontaneous Recovery Rates in Patients With Idiopathic Sudden Sensorineural Hearing Loss

Bayoumy

Veen

2018

JAMA Otolaryngol Head Neck Surg

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Idiopathic sudden sensorineural hearing loss (ISSHL) is an otolaryngologic emergency. The condition is usually defined as a sudden deafness of 30 dB or more in at least 3 contiguous frequencies that occurs in less than 3 days. 1 Pathologic causes need to be excluded. The origin is still unclear, but the main theories point to vascular or (viral) infectious diseases.According to the Cochrane Library and the American Academy of Otolaryngology guidelines, 2 the effectiveness and applicability of the most used medical therapies (ie, oral and intratympanic steroid monotherapy or corticosteroids in combination with hyperbaric oxygen) are still surrounded with doubt as to what constitutes the preferable treatment option.

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Is Corticosteroid Therapy Effective for Sudden-Onset Sensorineural Hearing Loss at Lower Frequencies?

Abstract: Corticosteroids were not effective for sudden-onset sensorineural hearing loss at lower frequencies.

Cited by 24 publications

References 7 publications

Trial of Chinese Medicine Wu-Ling-San for Acute Low-Tone Hearing Loss

Trial of Chinese Medicine Wu-Ling-San for Acute Low-Tone Hearing Loss

Sudden Onset Sensorineural Hearing Loss: Management Protocol

Assessment of Spontaneous Recovery Rates in Patients With Idiopathic Sudden Sensorineural Hearing Loss

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