Is Corticosteroid Therapy Effective for Sudden-Onset Sensorineural Hearing Loss at Lower Frequencies?

Abstract

Corticosteroids were not effective for sudden-onset sensorineural hearing loss at lower frequencies.

Discriminant Analysis of the Prognostic Factors for Hearing Outcomes in Patients with Idiopathic Sudden Sensorineural Hearing Loss

“…In our study, early treatment initiation was shown to be a favorable prognostic factor, which was also reported by Hamid et al 21 Plaza et al 22 and Kwon et al 23 However, Kitajiri et al 24 and Bayoumy et al 25 discovered an 81% spontaneous recovery rate in their control group. Particularly on the lower frequencies of SNHL, the spontaneous recovery rate might simulate a beneficial impact of treatment in the early stages of therapy.…”

Trial of Chinese Medicine Wu-Ling-San for Acute Low-Tone Hearing Loss

“…This resulted in about one quarter of our cases being probable cases. Previously, the peak age of ALHL onset was reported to be in the late 40s to 50s [1,2,4,7]. In our study, the mean age at onset was 47.3 years; however, the mean age of patients with definite ALHL was 40.1 years and that of patients with probable ALHL was 66.6 years.…”

“…In our study, the mean age at onset was 47.3 years; however, the mean age of patients with definite ALHL was 40.1 years and that of patients with probable ALHL was 66.6 years. In addition, the ratio of males:females has been reported as 1:2 to 1:3 [2,3,7]; among our definite cases the ratio was similar (32:89, or 1:2.8), but the ratio among our probable cases was almost 1:1. This shift from female predominance to equal frequency in both sexes suggests an age-related change in the pathogenesis of ALHL.…”

Differences in clinical characteristics and prognosis of sudden low‐ and high‐frequency hearing loss

“…Hui et al found that high‐dose glucocorticoid was more effective than a low dose in 44 LF patients, Mao and Wang reported that corticosteroid therapy probably had some effect on LF, and Fuse et al showed that a steroid was an effective therapy for LF . On the other hand, Kitajiri et al reported that corticosteroids were ineffective for improving hearing in 42 patients with LF, Morita et al showed that steroid–diuretic combination therapy was more effective than steroid or diuretic treatment alone, and Suzuki et al found that corticosteroid therapy, but not diuretic therapy, was effective in patients with LF . Alatas also recommended IT as an effective treatment for recovery in cases of LF and reported a complete recovery rate of 71.4% .…”