“…In general, predictors for low compliance to therapy include disease-related factors, such as treatment of chronic disease (Haynes et al, 2002;Jackevicius et al, 2002), treatment of asymptomatic disease (Sewitch et al, 2003), side effects of medication (van Servellen et al, 2002), complexity of treatment (Ammassari et al, 2002); psychological factors (Ammassari et al, 2002;Stilley et al, 2004), and cognitive impairment (Okuno et al, 2001;Stilley et al, 2004). Another group of factors that can affect drug compliance are related to contact with medical staff, such as poor physician-patient relationship (Urquhart, 2002;van Servellen et al, 2002), inadequate follow-up or discharge planning, and missed appointments (Lacro et al, 2002).…”