Is Appendicitis Decreasing in Frequency?

Castleton, Kenneth B.; Puestow, Charles B.; Sauer, Dean

doi:10.1001/archsurg.1959.04320050125019

Cited by 15 publications

(9 citation statements)

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“…To study time trends for the rates and identify significant changes between successive years, we first applied variance-stabilizing transformations on the data and then carried out asymptotic tests taking into consideration the correlation of the rates [2] . Significant percentage changes, i.e.…”

Section: Discussionmentioning

confidence: 99%

“…It has been suggested that the advent of antibiotics in the second half of the 20th century contributed to the fall of the acute appendicitis hospitalization rates [2,4] . However, the declining trend had started before antibiotics were widely available.…”

Section: Discussionmentioning

confidence: 99%

“…The diagnosis of appendicitis became more common in the last quarter of the 19th century. Death rates from the disease increased during the first quarter of the 20th century, peaked in the thirties and declined progressively thereafter [1][2][3][4] . Regarding the last 2 decades of the 20th century, in particular, most reports from western countries, including the UK [5][6][7][8] , the Netherlands [1] , Canada [9] , the USA [10,11] , Australia [12] and Sweden [13] , show further decrease of the incidence of appendicitis, although the decrease rate has been more modest.…”

Section: Introductionmentioning

confidence: 99%

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Dramatic Decline of Acute Appendicitis in Greece over 30 Years: Index of Improvement of Socioeconomic Conditions or Diagnostic Aids?

Papadopoulos

Polymeros

Kateri

et al. 2008

Dig Dis

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Background and Aims: There are several reports showing a continuing fall in the incidence of acute appendicitis in the western countries. Our aim was to study the trend of the incidence of acute appendicitis in the Greek population over 30 years. Methods: We analyzed the data referring to the years 1970–1999 on the incidence and mortality of acute appendicitis for the entire Greek population. Data were retrieved from the Annual Bulletin for the Social Welfare and Health Statistics of the National Statistics Service of Greece. In this database, acute appendicitis was a hospital discharge diagnosis. Results: Over the study period, there was a 75% decrease of the age-standardized incidence of acute appendicitis from 652/100,000 to 164/100,000. The median female-to-male ratio of hospitalized patients for appendicitis of the study period (1970–1999) fell progressively from 1.27 in the year 1970 to 0.93 in the year 1999. The case fatality rates remained constant, ranging below 0.09 deaths per 100 appendicitis cases. Conclusion: There is a significant decline of the incidence of acute appendicitis in the Greek population over the years 1970–1999. This time trend is probably related to the improvement of the socioeconomic conditions over the same period and not to the introduction of new diagnostic aids.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Dramatic Decline of Acute Appendicitis in Greece over 30 Years: Index of Improvement of Socioeconomic Conditions or Diagnostic Aids?

Papadopoulos

Polymeros

Kateri

et al. 2008

Dig Dis

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show abstract

“…Although acute appendicitis was recognized as a clinical entity as long ago as 17591, Fitz, in 1886, was the first investigator to use the term ‘appendicitis’2, which became an important clinical problem by the end of the 19th century3, 4. Death rates peaked in the 1910s to the 1930s, and thereafter progressively declined5, 6. Even so, acute appendicitis remains one of the commonest conditions leading to operation in western countries7, although it is less common in developing countries8.…”

Section: Introductionmentioning

confidence: 99%

“…Even so, acute appendicitis remains one of the commonest conditions leading to operation in western countries7, although it is less common in developing countries8. In Britain and the USA, acute appendicitis has declined in frequency since the 1930s, but most published studies have covered periods up to only around 19906, 9–16.…”

Section: Introductionmentioning

confidence: 99%