“Is anemia frequently recognized in gastroschisis compared to omphalocele? A multicenter retrospective study in southern Japan” by Sugita, K et al

Govani, D.J.; Trambadia, Rajvi Anilkumar; Chhaniara, Rohan Ashit; Mirani, Zankhan Ramkishan; Midha, Partap Kumar; Correia, Rafael Cavalcante; Patel, Ramnik V

doi:10.1007/s00383-022-05288-8

Cited by 3 publications

(2 citation statements)

References 1 publication

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“…It has been reported in adults but it is rare to see in elderly patients [13]. This can lead to chronic fecal retention leading to dysbiosis of colon, intermittent or continuous ileocecal reflux, small bowel bacterial overgrowth with activation of the immune system network via Payer's patches and causing malabsorption with multiple micronutrient deficiency [14,15].…”

Section: Discussionmentioning

confidence: 99%

Hypoganglionosis and Isolated Crohn’s Disease of the Terminal Ileum Presenting with Perforation Mimicking Appendicular Mass in a 72-Year-Old Asian Lady

Govani,

Zaparackaite,

Jit Singh

et al. 2023

SciBase Crit Care Emerg Med

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A very unusual and interesting case of a 72-year-old Indian female with a background of chronic constipation since early infancy presented in emergency critical condition with acute perforative peritonitis and right lower quadrant fullness, guarding and tenderness. Laboratory studies showed high inflammatory markers and provisional diagnosis of walled off appendicular perforation was made. Radiographs and multi scanner computed tomography (MSCT) was found to have pneumoperitoneum secondary to the terminal ileal stricture with perforation. The patient underwent emergency exploratory laparotomy following initial resuscitation, resection and anastomosis of the ileal stricture, peritoneal toilet and extramucosal biopsies of rectosigmoid colon were performed. Histopathology confirmed isolated Crohn’s disease of terminal ileum with stricture and associated hypoganglionosis. Subsequent colonoscopy and biopsies showed no active Crohn’s disease but had nonspecific colitis of the left colon due to associated hypoganglionosis. The postoperative period was uneventful. The patient is doing well at follow up with conservative management of the hypoganglionosis with laxatives, dietary changes, life style modifications and dietary supplements.

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Section: Discussionmentioning

confidence: 99%

Hypoganglionosis and Isolated Crohn’s Disease of the Terminal Ileum Presenting with Perforation Mimicking Appendicular Mass in a 72-Year-Old Asian Lady

Govani,

Zaparackaite,

Jit Singh

et al. 2023

SciBase Crit Care Emerg Med

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show abstract

“…Our team has extensive experience of dealing with pelvic outlet triple colorectal, genital and urinary systems anatomical diseases and functional disorders, congenital and acquired involving anatomical and functional problems [1][2][3][4][5][6][7][8][9][10][11][12]. However, we have never come across such an exciting case involving all three major pelvic outlet systems and implications with regards to the diagnosis and subsequent therapeutic interventions.…”

Section: Introductionmentioning

confidence: 99%

Successful Conservative Management of Triple Pelvic Outlet Functional Obstruction Syndrome with Voiding, Menstrual and Bowel Dysfunctions in an Adolescent Girl with long term follow up

Patel

2023

JUNS

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Triple pelvic outlet functional obstruction syndrome or dysfunctional elimination syndrome is a collective name given to the urinary, genital and colorectal dysfunction of the psycho-neuro-endocrine-target organs axis origin secondary to congenital and acquired disorders characterized by functional pelvic outlet obstruction in the absence of any somatic neurologic deficits. We wish to report an adolescent girl with a voiding dysfunction leading to recurrent urinary tract infection, vesicoureteral reflux and declining renal function; very painful, heavy and irregular periods and chronic refractory constipation who was successfully managed free of cost remotely by conservative management using biofeedback, dietary, micronutrient and pelvic outlet elimination retraining with a long term follow up over a decade without any recurrence of symptoms.

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An Innovative Therapy by Changing the Gut Microbiome for the Dual Post-Operative Complications of the Recurrent Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in the Residual Type II First Branchial Cyst and Facial Nerve Palsy

Govani,

Zaparackaite,

Singh

et al. 2023

Heighpubs Otolaryngol Rhinol

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A very unusual, interesting, and challenging case of a 24-year-old female who was born with three openings in the neck. The patient had chronic abdominal gaseous distention, recurrent abdominal pain, and constipation since early infancy. The patient presented in emergency with acute painful red, hot, and tender swelling in the left upper cervical area. Laboratory studies showed high inflammatory markers and a provisional diagnosis of abscess with a sinus was made. The patient underwent an emergency incision and drainage. Sinus recurred and a sinogram showed it to be a residual cyst in the left submandibular salivary gland. The total cyst excision was attempted with resultant recurrence and grade IV facial nerve palsy. Post-operatively recurrent infections caused by Methicillin-resistant Staphylococcus aureus (MRSA) required several courses of oral and intravenous broad-spectrum antibiotics with several hospital admissions with no resolution in sight. Subsequent ultrasound and magnetic resonance imaging showed a residual infected cyst, cutaneous sinus, and a fistula opening in the left ear canal. A diagnosis of branchial cyst type II of the first brachial cleft remnant with a fistula was established with bilateral branchial fistulas of the second branchial remnants and the associated colorectal hypoganglionosis based on radiological studies. The patient refused any further operative interventions. Therefore, the option of conservative treatment of hypoganglionosis with holobiotics consisting of prebiotics, probiotics and postbiotics, laxatives, dietary changes, lifestyle modifications, and dietary supplements started. All antibiotics were stopped. These therapies resulted in the resolution of residual first branchial remnants and recurrent MRSA infections with the improvement in the facial nerve palsy from grade IV to grade III-IV together with an excellent cosmetic and functional result. The patient is doing well at follow-ups being infection-free for 18 months and repeat contrast-enhanced computed tomogram (CECT) has shown complete resolution of the residual cyst, sinus, and fistula with fibrosis.

show abstract

“Is anemia frequently recognized in gastroschisis compared to omphalocele? A multicenter retrospective study in southern Japan” by Sugita, K et al

Cited by 3 publications

References 1 publication

Hypoganglionosis and Isolated Crohn’s Disease of the Terminal Ileum Presenting with Perforation Mimicking Appendicular Mass in a 72-Year-Old Asian Lady

Hypoganglionosis and Isolated Crohn’s Disease of the Terminal Ileum Presenting with Perforation Mimicking Appendicular Mass in a 72-Year-Old Asian Lady

Successful Conservative Management of Triple Pelvic Outlet Functional Obstruction Syndrome with Voiding, Menstrual and Bowel Dysfunctions in an Adolescent Girl with long term follow up

An Innovative Therapy by Changing the Gut Microbiome for the Dual Post-Operative Complications of the Recurrent Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in the Residual Type II First Branchial Cyst and Facial Nerve Palsy

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