Is a Sexual Dysfunction Domain Important for Quality of Life in Men with Urological Chronic Pelvic Pain Syndrome? Signs “UPOINT” to Yes

Davis, Seth N.P.; Binik, Yitzchak M.; Amsel, Rhonda; Carrier, Serge

doi:10.1016/j.juro.2012.08.083

Cited by 47 publications

(41 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The modified UPOINTs algorithm has been suggested to support an optimized stratification of individual phenotypic profiles. However, clinical studies attempting to confirm an improved correlation between positive UPOINTs domains and symptom severity revealed heterogeneous results [48,[55][56][57].…”

Section: Treatment Of Chronic Prostatitis/chronic Pelvic Pain Syndromementioning

confidence: 99%

Contemporary Management of Chronic Prostatitis/Chronic Pelvic Pain Syndrome

et al. 2016

View full text Add to dashboard Cite

Section: Treatment Of Chronic Prostatitis/chronic Pelvic Pain Syndromementioning

confidence: 99%

Contemporary Management of Chronic Prostatitis/Chronic Pelvic Pain Syndrome

et al. 2016

View full text Add to dashboard Cite

“…There may also be an association with recurrent UTIs in a minority of patients [19,21] Voiding LUTS (weak stream, straining and hesitancy) Storage LUTS (urgency AE urge incontinence, increased urinary frequency, nocturia and dysuria) Urethral burning during, and independent of, micturition Haematospermia (blood in semen) Recurrent UTI (more applicable to CBP) Sexual dysfunction symptoms [17,[22][23][24][25][26][27][28][29][30] Findings from cohort studies (n = 130-1 800) indicate that total or partial ED is reported by 15-55% of patients with CP/CPPS [22,[31][32][33][34], while the prevalence of overall, self-reported sexual dysfunction is higher at 46-92% [22,23,31,34]. Correlation studies of sexual dysfunction symptoms with NIH-CPSI scores indicate that patients with CP/CPPS with sexual dysfunction have higher total and QoL scores, suggesting that sexual symptoms can contribute substantially to morbidity [28,[31][32][33]35,36].…”

Section: Clinical Assessment and Diagnosismentioning

confidence: 99%

Diagnosis and treatment of chronic bacterial prostatitis and chronic prostatitis/chronic pelvic pain syndrome: a consensus guideline

Rees

Abrahams

Doble³

et al. 2015

BJU International

241

193

View full text Add to dashboard Cite

ObjectivesTo improve awareness and recognition of chronic bacterial prostatitis (CBP) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) among non-specialists and patients. To provide guidance to healthcare professionals treating patients with CBP and CP/CPPS, in both non-specialist and specialist settings. To promote efficient referral of care between nonspecialists and specialists and the involvement of the multidisciplinary team (MDT). Patients and MethodsThe guideline population were men with CBP or CP/CPPS (persistent or recurrent symptoms and no other urogenital pathology for ≥3 of the previous 6 months). Consensus recommendations for the guidelines were based on a search to identify literature on the diagnosis and management of CBP and CP/CPPS (published between 1999 and February 2014). A Delphi panel process was used where high-quality, published evidence was lacking. ResultsCBP and CP/CPPS can present with a wide range of clinical manifestations. The four main symptom domains are urogenital pain, lower urinary tract symptoms (LUTSvoiding or storage symptoms), psychological issues and sexual dysfunction. Patients should be managed according to their individual symptom pattern. Options for first-line treatment include antibiotics, a-adrenergic antagonists (if voiding LUTS are present) and simple analgesics. Repeated use of antibiotics, such as quinolones, should be avoided if there is no obvious symptomatic benefit from infection control or cultures do not support an infectious cause. Early use of treatments targeting neuropathic pain and/or referral to specialist services should be considered for patients who do not respond to initial measures. An MDT approach (urologists, pain specialists, nurse specialists, specialist physiotherapists, general practitioners, cognitive behavioural therapists/psychologists, and sexual health specialists) is recommended. Patients should be fully informed about the possible underlying causes and treatment options, including an explanation of the chronic pain cycle. ConclusionChronic prostatitis can present with a wide variety of signs and symptoms. Identification of individual symptom patterns and a symptom-based treatment approach are recommended. Further research is required to evaluate management options for CBP and CP/CPPS.

show abstract

“…The clinical domains of UPOINT are Urinary symptoms, Psychosocial dysfunction, Organ-specific findings, Infection, Neurologic/systemic conditions, and Tenderness of muscles, providing mnemonic UPOINT. With sexual dysfunction affecting 40-70% of all men with CP/CPPS [39][40][41], the inclusion of an additional domain for sexual dysfunction was proposed, and a modified UPOINT algorithm (UPOINTs) has been suggested [42][43][44].…”

Section: Prudent Approach To Chronic Pelvic Pain In Malesmentioning

confidence: 99%

Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Male Bladder Pain Syndrome/Interstitial Cystitis: How Are They Related?

Lee

2017

Urogenit Tract Infect

View full text Add to dashboard Cite

To date, the heterogeneous pathophysiology of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and bladder pain syndrome/interstitial cystitis (BPS/IC) has not been fully elucidated. Thus, it is difficult to make a full comparison between CP/CPPS and male BPS/IC. Controversy and confusion surrounding the terminologies and classifications of CP/CPPS and BPS/IC complicates the issue. CP/CPPS and male BPS/IC are not mutually exclusive conditions, in that they have similarities in their pathogenesis and clinical presentation. Based on the working definitions of these terms, it would be correct to say that male BPS/IC is subsumed by CP/CPPS, and that male BPS/IC can be regarded as CP/CPPS with clear bladder-specific features. Although the term CP/CPPS may be inappropriate, especially since "CP" may be misleading, the perspective that CP/CPPS and male BPS/IC are male urological chronic pain syndromes could enhance the understanding of the relationship between the two. The European Association of Urology classification for chronic pelvic pain is systematic and corresponds well with our knowledge of chronic pain. Therefore, this classification might be the solution to the problems associated with the existing terminologies and taxonomy of CP/CPPS and BPS/IC. In the management of urological chronic pelvic pain in men, clinical phenotyping systems (the UPOINT or UPOINTs system) profile patients and indicate how tailored treatment could be achieved as individualized, multimodal therapeutic regimens. It would be prudent to include bladder-specific features, such as painful filling or painful urgency, in the criteria for the organ-specific domain of the UPOINT(s) system.

show abstract

Is a Sexual Dysfunction Domain Important for Quality of Life in Men with Urological Chronic Pelvic Pain Syndrome? Signs “UPOINT” to Yes

Abstract: Adding a sexual dysfunction domain to UPOINT may help improve quality of life in men treated for urological chronic pelvic pain syndrome.

Cited by 47 publications

References 25 publications

Contemporary Management of Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Contemporary Management of Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Diagnosis and treatment of chronic bacterial prostatitis and chronic prostatitis/chronic pelvic pain syndrome: a consensus guideline

Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Male Bladder Pain Syndrome/Interstitial Cystitis: How Are They Related?

Contact Info

Product

Resources

About