Is a new COVID‐19 wave coming from China due to an unknown variant of concern? Keep calm and look at the data

Branda, Francesco; Scarpa, Fabio; Ciccozzi, Massimo; Maruotti, Antonello

doi:10.1002/jmv.28601

Cited by 4 publications

(4 citation statements)

References 21 publications

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“…Mortality rates and changes in human mobility, measured through aggregate data, aided modeling efforts 26. To enable evidence-based responses, efficient and secure data sharing is essential, supporting tasks from monitoring variants to vaccine strain selection 27. To achieve these goals, collaboration among diverse partners, is crucial for a multidisciplinary, multisectoral network that embraces a "One Health" perspective.…”

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confidence: 99%

Epidemic history and evolution of an emerging threat of international concern, the severe acute respiratory syndrome coronavirus 2

Giovanetti,

Branda,

Cella

et al. 2023

Journal of Medical Virology

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This comprehensive review focuses on the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and its impact as the cause of the COVID‐19 pandemic. Its objective is to provide a cohesive overview of the epidemic history and evolutionary aspects of the virus, with a particular emphasis on its emergence, global spread, and implications for public health. The review delves into the timelines and key milestones of SARS‐CoV‐2's epidemiological progression, shedding light on the challenges encountered during early containment efforts and subsequent waves of transmission. Understanding the evolutionary dynamics of the virus is crucial in monitoring its potential for adaptation and future outbreaks. Genetic characterization of SARS‐CoV‐2 is discussed, with a focus on the emergence of new variants and their implications for transmissibility, severity, and immune evasion. The review highlights the important role of genomic surveillance in tracking viral mutations linked to establishing public health interventions. By analyzing the origins, global spread, and genetic evolution of SARS‐CoV‐2, valuable insights can be gained for the development of effective control measures, improvement of pandemic preparedness, and addressing future emerging infectious diseases of international concern.

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confidence: 99%

Epidemic history and evolution of an emerging threat of international concern, the severe acute respiratory syndrome coronavirus 2

Giovanetti,

Branda,

Cella

et al. 2023

Journal of Medical Virology

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“…Of course, this must not be understood as a reason to let our guard down against the pandemic, but the fear must not cloud the judgment, and decisions must be made based on data 12 . As pointed out by Akif et al 11 “ … we should not give the virus any chance to control our lives .” Indeed, genome‐based monitoring must continue uninterruptedly to be prepared and well‐documented on the real situation.…”

Section: Figurementioning

confidence: 99%

“…In conclusion, genetic and structural data on SARS‐CoV‐2 BF.7 here presented suggest that this new variant currently does not show evidence of a likely high expansion capability. It is very common in Asia, but it appears less virulent than other Omicron variants 11 . Although BF.7 (and in particular the R346 mutation) has been associated to the immune escape capability to neutralize antibodies (https://www.cbsnews.com/news/bf7-new-omicron-coronavirus-variant-covid/), as of now, it does not show evidence of its particular dangerous or high expansion capability.…”

Section: Figurementioning

confidence: 99%

“…It is very common in Asia, but it appears less virulent than other Omicron variants. 11 Although BF.7 (and in particular the R346 mutation) has been associated to the immune escape capability to neutralize antibodies (https://www.cbsnews.com/news/bf7-new-omicron-coronavirusvariant-covid/), as of now, it does not show evidence of its particular dangerous or high expansion capability. Also, in this case, the features that may be theoretically related to advantages are due to genetic drift that allows to the virus a constant adaptability to the host but is not strictly connected to a fitness advantage.…”

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confidence: 99%

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Genome‐based survey of the SARS‐CoV‐2 BF.7 variant from Asia

Scarpa

Giovanetti

Azzena

et al. 2023

Journal of Medical Virology

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The SARS-CoV-2 BF.7 variant represents one of the most recent subvariant under monitoring. At the beginning of the 2023 it caused several concerns especially in Asia because of a resurge in COVID-19 cases. Here we perform a genome-based integrative approach on SARS-CoV-2 BF.7 to shed light on this emerging lineage and produce some consideration on its real dangerousness. Both genetic and structural data suggest that this new variant currently does not show evidence of an high expansion capability. It is very common in Asia, but it appears less virulent than other Omicron variants as proved by its relatively low evolutionary rate (5.62 × 10 −4 subs/ sites/years). The last plateau has been reached around December 14, 2022 and then the genetic variability, and thus the viral population size, no longer increased. As already seen for several previous variants, the features that may be theoretically related to advantages are due to genetic drift that allows to the virus a constant adaptability to the host, but is not strictly connected to a fitness advantage. These results have further pointed that the genome-based monitoring must continue uninterruptedly to be prepared and well documented on the real situation.

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Prevalence, outcomes and associated factors of SARS-CoV-2 infection in psoriasis patients of Southwest China: a cross-sectional survey

Zou,

Xu,

Chen

et al. 2024

Sci Rep

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In this study we aimed to investigate the prevalence of SARS-CoV-2 infection in psoriasis patients, and outcomes of SARS-CoV-2 infection and associated risk factors. A cross-sectional survey was conducted from February 2023 to March 2023. Information was obtained with online questionnaire about psoriasis patients on demographic characteristics, clinical characteristics, SARS-CoV-2 infection and outcomes, vaccination, and routine protection against COVID-19. Logistic regression analysis was used to explore risk factors with SARS-CoV-2 infection and exacerbation of psoriasis. A total of 613 participants were recruited. 516 (84.2%) were infected, and associated factors were sex, working status, routine protection against COVID-19, COVID-19 vaccination, impaired nail, infection exacerbate psoriasis, and severity of psoriasis. Among the patients infected with SARS-CoV-2, 30 (5.8%) required hospitalization, 122 (23.6%) had psoriasis exacerbation due to SARS-CoV-2 infection, and associated factors were subtype of psoriasis, discontinuation of psoriasis treatment during SARS-CoV-2 infection, response following COVID-19 vaccination, and severity of psoriasis. Booster dose vaccination contributed a low probability of COVID-19 sequelae. COVID-19 vaccine’s effectiveness was unsatisfactory, while booster dose vaccination reduced the occurrence of COVID-19 sequelae in psoriasis patients of Southwest China. Patients treated with psoriasis shown to be safe, without a higher incidence of SARS-CoV-2 infection or COVID-19hospitalization compared to untreated patients. Stopping treatment during SARS-CoV-2 infection led to psoriasis exacerbation, so psoriasis treatment could be continued except severe adverse reaction.

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Is a new COVID‐19 wave coming from China due to an unknown variant of concern? Keep calm and look at the data

Cited by 4 publications

References 21 publications

Epidemic history and evolution of an emerging threat of international concern, the severe acute respiratory syndrome coronavirus 2

Epidemic history and evolution of an emerging threat of international concern, the severe acute respiratory syndrome coronavirus 2

Genome‐based survey of the SARS‐CoV‐2 BF.7 variant from Asia

Prevalence, outcomes and associated factors of SARS-CoV-2 infection in psoriasis patients of Southwest China: a cross-sectional survey

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