Irritation of the human eye mucous membrane caused by airborne pollutants

Abstract

It is concluded that the type of exposure made no difference to the elicited physiological responses and that tear film stability and epithelium damage were not affected by sensory irritation itself.

Eye irritation and environmental factors in the office environment-hypotheses, causes and a physiological model

“…For example, a butyl acetate concentration of 1400 mg/m 3 has resulted in a significant increase, from 9 to 12 blinks/ minute, although the break-up time remained unchanged (81). [For comparison see reference 82.] Exposure to a mixture of VOC (12-24 mg/m 3 ) resulted in a dose or time-dependent increase in blink frequency that was associated with eye irritation (83).…”

Cutoff in detection of eye irritation from vapors of homologous carboxylic acids and aliphatic aldehydes

“…We stress that all stimuli presented were at the very border of detection/no detection. Such brief and barely detectable stimulation levels do not produce clinical ocular signs (Podlekareva et al, 2002). After testing each triad, subjects were required to select the presentation that felt "different" (typically stronger) from the other two, guessing if necessary, and to rate the confidence in their decision on a scale from "1" (not confident at all) to "5" (extremely confident).…”

An experimental parametric study of VOC from flooring systems exposed to alkaline solutions

“…On alkaline hydrolysis, the alcohols 2-ethyl-1-hexanol and n-butanol, and other compounds may be formed and emitted from the material (Alexandersson, 2003(Alexandersson, , 2004Bjo¨rk et al, 2003;Persson, 2002;Sjo¨berg, 2001;Wilke et al, 2004). These specific degradation products have been found correlated with increased SBS symptoms in damp buildings (Nordstro¨m et al, 1999) and cause irritation of the human mucous membrane (Podlekareva et al, 2002), and are good tracers of decomposition of the flooring materials because of alkaline hydrolysis.…”