Irradiation of the cervix uteri: value of unenhanced and contrast-enhanced MR imaging.

Hricak, Hedvig; Swift, Patrick S.; Campos, Zelia; Quivey, Jeanne M.; Gildengorin, Virginia; Göranson, H.

doi:10.1148/radiology.189.2.8210364

Cited by 84 publications

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“…However, the early detection of recurrent disease in the pelvis may pose a diagnostic challenge. The symptoms can be nonspecific, and physical examination of the irradiated pelvis is often limited (3). In addition, cytological examination of the irradiated cervix has a poor sensitivity for detecting tumor recurrence, ranging from 28% to 51% (4,5).…”

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confidence: 99%

“…In a study of patients with cervical cancer treated with radiotherapy, Hricak et al (3) reported that T2-weighted imaging is better than nonenhanced or nondynamic contrastenhanced T1-weighted imaging for detection of tumor recurrence. However, other studies have questioned the accuracy of T2-weighted MR imaging to distinguish between tumor recurrence and posttherapy fibrosis (6 -10).…”

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confidence: 99%

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Evaluation of locally recurrent pelvic malignancy: Performance of T2‐ and diffusion‐weighted MRI with image fusion

Nishie

Stolpen

Obuchi

et al. 2008

Magnetic Resonance Imaging

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Purpose:To evaluate the performance of T2-and diffusionweighted magnetic resonance imaging (MRI) with image fusion for detection of locally recurrent pelvic malignancy. Materials and Methods:The study group consisted of 28 patients (27 female, 1 male) who underwent pelvic MRI at 1.5 T after treatment of pelvic malignancy. MR images were reviewed independently by three blinded readers. The performance of the four sequences for detecting local recurrence was evaluated using receiver operating characteristic analysis: T2-weighted fast spin-echo (FSE), diffusionweighted echo-planar imaging (DWI), dynamic contrast-enhanced (DCE) fat-suppressed T1-weighted spoiled gradient echo (SPGR), and T2-DWI with image fusion, the latter created using OsiriX Medical Imaging Software.Results: Local recurrence was confirmed at biopsy in 16 patients. Twelve patients showed no evidence of recurrence on two consecutive MRI studies. The Az value for T2-DWI with image fusion (0.949) was statistically greater than that for T2-weighted FSE (0.849) (P Ͻ 0.05). The sensitivity and specificity was 87.5% and 47.2%, respectively, for T2-weighted FSE, 100.0% and 50.0% for DWI, 95.8% and 58.3% for DCE fat-suppressed T1-weighted SPGR, and 93.8% and 72.2% for T2-DWI with image fusion. Conclusion:For depicting locally recurrent pelvic malignancy, T2-DWI with image fusion outperforms standard T2-weighted FSE and DWI and is comparable to DCE fatsuppressed T1-weighted SPGR.

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confidence: 99%

mentioning

confidence: 99%

Evaluation of locally recurrent pelvic malignancy: Performance of T2‐ and diffusion‐weighted MRI with image fusion

Nishie

Stolpen

Obuchi

et al. 2008

Magnetic Resonance Imaging

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“…Parametrial fi brosis displaying low SI on T2WI is most evident in areas of previous tumor invasion (Engin 2006 ). Complete reconstitution of the normal cervical anatomy and low SI of cervical stroma indicate tumor-free status (97 % PPV for exclusion tumor recurrence) (Hricak et al 1993 ). However, particularly, within the fi rst 3 months of treatment, differentiation between residual tumor and postirradiation changes is not possible (Engin 2006 ).…”

Section: Cervix and Vaginamentioning

confidence: 99%

“…9 ), but cyclic changes of folliculogenesis may resume. Hydrosalpinx caused by tubal obstruction may be seen after hysterectomy and uterine radiation therapy, both in pre-and postmenopausal age (Hricak et al 1993 ).…”

Section: Ovariesmentioning

confidence: 99%

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Female Pelvis: Genital Organs

Forstner

Cunha²

2015

Imaging of Complications and Toxicity Following Tumor Therapy

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Medical Radiology-Diagnostic Imaging is a unique series that aims to document the most innovative technologies in all fi elds within diagnostic imaging and interventional radiology, thereby informing the physician in practice of the latest advances in diagnostic imaging and percutaneous imageguided minimally invasive procedures. Th e contents are intended to cover all organs, and all modern imaging techniques and image-guided treatment modalities, with special emphasis on applications in clinical practice. Each volume is a comprehensive reference book on a topical theme, and the editors are always experts of high international standing. Contributions are included from both clinicians and researchers, ensuring wide appeal. Medical Radiology -Radiation Oncology is a unique series that aims to document the most innovative technologies in all fi elds within radiology, thereby informing the physician in practice of the latest advances in diagnostic and treatment techniques. Th e contents range from contemporary statements relating to management for various disease sites to explanations of the newest techniques for tumor identifi cation and of mechanisms for the enhancement of radiation eff ects, with the emphasis on maximizing cure and minimizing complications. Each volume is a comprehensive reference book on a topical theme, and the editors are always experts of high international standing. Contributions are included from both clinicians and researchers, ensuring wide appeal. This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifi cally the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfi lms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specifi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. AbstractA precise knowledge of antineoplastic drugs is an indispensable basis for the care of patients with cancer. The mechanisms of action and resistance, cross-resistance patterns, pharmacodynamics and pharmacokinetics, pharmacological interaction, and last but not least potential adverse effects should be part of this knowledge. As contemporary cancer care requires interdisciplinary and multiprofessional structures, the radiologist is an important a...

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Pelvis MRI: Introduction and Technique

Brown¹,

Semelka²

2014

Women's Imaging

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Irradiation of the cervix uteri: value of unenhanced and contrast-enhanced MR imaging.

Abstract: Overall, diagnosis was best with unenhanced T2-weighted images, but in patients with adnexal or pelvic sidewall recurrence and in patients with treatment complications (eg, fistula formation), contrast enhancement did help.

Cited by 84 publications

References 0 publications

Evaluation of locally recurrent pelvic malignancy: Performance of T2‐ and diffusion‐weighted MRI with image fusion

Evaluation of locally recurrent pelvic malignancy: Performance of T2‐ and diffusion‐weighted MRI with image fusion

Female Pelvis: Genital Organs

Pelvis MRI: Introduction and Technique

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