Irradiation of cells in tissue culture

Pomerat, C. M.; Kent, Sidney P.; Logie, Loren C.

doi:10.1007/bf00340146

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1971

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Cited by 45 publications

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“…In the present paper we describe some morphological changes visible in the phase contrast and in the histological sections of these cells fixed in a tllin layer on the spleen. Similar changes were observed by Pomerat, Kent and Logie (1957) after irradiation of HeLa cells with doses of 2000-4000 rads. We also have found clusters of nuclear masses, formed into a shape very similar to that of chromosomes.…”

Section: Discussionsupporting

confidence: 80%

“…We also have found clusters of nuclear masses, formed into a shape very similar to that of chromosomes. These formations, resembling seriously damaged mitoses, we observed after radiation doses that greatly exceeded those used by Pomerat et al (1957) and by Nias and Paul (1961). Obviously, even doses of 100,000 rads do not exert an immediate lethal effect on all EAT cells, at least when put into optimal life-conditions.…”

Section: Discussionsupporting

confidence: 50%

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