Iron-sulfur protein odyssey: exploring their cluster functional versatility and challenging identification
Cindy Vallières,
Orane Benoit,
Olivier Guittet
et al.
Abstract:Iron-sulfur (Fe-S) clusters are an essential and ubiquitous class of protein-bound prosthetic centers that are involved in a broad range of biological processes (e.g. respiration, photosynthesis, DNA replication and repair and gene regulation) performing a wide range of functions including electron transfer, enzyme catalysis, and sensing. In a general manner, Fe-S clusters can gain or lose electrons through redox reactions, and are highly sensitive to oxidation, notably by small molecules such as oxygen and ni… Show more
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