Iron oxides in human spleen

Kopáni, Martin; Miglierini, Marcel; Lančok, Adriana; Dekan, Július; Čaplovičová, Mária; Jakubovský, J; Boča, Roman; H, Mrázová

doi:10.1007/s10534-015-9876-2

Cited by 29 publications

(12 citation statements)

References 43 publications

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“…It has become routinely performed on a wide range of different types of samples such as ultrathin films [1,2,3,4,5,6], nanoparticles [7,8,9,10,11], nanowires [12,13], nanocomposites [14], quantum dots [15], graphene [16,17], dilute magnetic [18,19,20,21,22], and ferromagnetic semiconductor epilayers [23,24]. It currently enters the realms of organic spintronics [25], biology [26], and arXiv:1809.02346v3 [cond-mat.mtrl-sci] 5 Jul 2019…”

Section: Introductionmentioning

confidence: 99%

In situ compensation method for high-precision and high-sensitivity integral magnetometry

Gas

Sawicki

2019

Meas. Sci. Technol.

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The ongoing process of the miniaturization of spintronics and magneticfilms-based devices, as well as a growing necessity for basic material research place stringent requirements on sensitive and accurate magnetometric measurements of minute magnetic constituents deposited on large magnetically responsive carriers. However, the ever so popular commercial integral magnetometers based on superconducting quantum interference device sensor are not object-selective probes. Therefore, the sought signal is usually buried in the magnetic response of the carrier, contaminated by signals from the sample support, system instabilities and additionally degraded by inadequate data reduction. In this report a comprehensive method based on in situ magnetic compensation by sample abutting long strips made of matching material is shown to provide means for mitigating all these weak elements of integral magnetometry. Practical solutions and proper expressions to calculate the absolute values of the investigated moments are given. Their universal form allows to employ the suggested design in investigations of a broad range of specimens of different sizes, shapes and compositions. The method does not require any extensive numerical modeling, relying only on the data provided by the magnetometer. The solution can be straightforwardly implemented in every field where magnetic investigations are of a prime importance, including the emerging new fields of topological insulators, 3D-Dirac semimetals and 2D-materials.

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Section: Introductionmentioning

confidence: 99%

In situ compensation method for high-precision and high-sensitivity integral magnetometry

Gas

Sawicki

2019

Meas. Sci. Technol.

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“…In our previous work we studied iron distribution and magnetic properties in the human spleen and in G. pallidus of the human brain and their relationships to glycoconjugates [20,21]. The aim of this study is to investigate the magnetic properties of these iron deposits by the Superconducting Quantum Interference Device (SQUID) and asset the effect of glycoconjugates microenvironment.…”

Section: Introductionmentioning

confidence: 99%

Magnetic Properties of Iron Oxides in the Human Globus pallidus

Kopáni¹,

Hlinkova²,

Ehrlich³

et al. 2017

J Bioanal Biomed

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Postmortem brain tissue sections from Globus pallidus externus were routinely obtained during the autopsy to prepare tissue sections for the pathology diagnosis at Department of pathology, Comenius University, Bratislava. Tissues were taken from individuals without clinical findings of any motor abnormalities, iron metabolism, movements involving limbs, face, and tongues (Table 1). All procedures were conducted in accordance with the Declaration of Helsinki. AbstractSeveral types of iron oxides can be found in the various parts of the human brain. These can be highlighted in the light microscopy and using scanning or transmission mode of the electron microscopy. Some of them are non-magnetic, some, on the contrary, display magnetic response. It is not clear which kind of magnetic particles are accumulated in the human brain as inorganic deposits. Light microscopy, electron microscopy and sensitive Superconducting Quantum Interference Device (SQUID magnetometer) were used in order to detect iron deposits and their magnetic response in the samples extracted from the Globus pallidus of the human brain. Electron microscopy reveals a presence of the single crystals of hematite (α-Fe 2 O 3 ) of the size up to 1000 nm in the samples extracted from G. pallidus because of the diffractograms characteristic for the hexagonal unit cell; this mineral offers basically a diamagnetic response. The temperature dependence of the magnetic susceptibility allows a classification of the samples into three groups: mostly diamagnetic I, prevailing paramagnetic III, and an intermediate class II. The bulk samples exhibit a long-range magnetic ordering with magnetic hysteresis evidenced not only at low temperature but also at the room temperature. The recorded magnetic functions refer either to the presence of magnetite (Fe 3 O 4 ), or maghemite (γ-Fe 2 O 3 ). Iron oxides and oxidohydroxides found as inorganic deposits in the human brain can result from interaction between iron and microenvironment in the form of polysaccharides of glycoconjugates. They display magnetoactivity characteristic for magnetite and/or maghemite.

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“…Investigation of magnetic properties of several animal and/or human organs brought important information that some deposits of the iron oxides are present in them, at least in spleen (Boča et al 2013;Kopáni et al 2015) and brain (Kirschvink et al 1992;Makohusová et al 2014;Dlháň et al 2018). These deposits consist of hematite -Fe2O3 (antiferromagnetic), maghemite…”

Section: Introductionmentioning

confidence: 99%

Magnetic response of bovine spleen

Dlháň¹,

Krylov²,

Kopáni³

et al. 2019

Nova Biotechnologica Et Chimica

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Bovine spleen has been used as a sample for deep magnetochemical investigation. Temperature dependence of the magnetic susceptibility and field dependence of the magnetization reveal a paramagnetic behaviour that violates the Curie law. The zero-field cooled magnetization and field cooled magnetization experiments show the bifurcation point at ca TC = 20 K and the blocking temperature TB = 10 K confirming a dominating portion of ferritin along with the organic tissue. There is a remnant magnetization at temperature below 20 K and the search for the magnetic hysteresis was positive.

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Iron oxides in human spleen

Cited by 29 publications

References 43 publications

In situ compensation method for high-precision and high-sensitivity integral magnetometry

In situ compensation method for high-precision and high-sensitivity integral magnetometry

Magnetic Properties of Iron Oxides in the Human Globus pallidus

Magnetic response of bovine spleen

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