Iron Deficiency in Comorbidity Chronic Heart Failure and Diabetes Mellitus

Abstract

The clinical significance of iron deficiency in patients with a combination of heart failure and diabetes mellitus has not been studied. 67 patients with chronic heart failure and diabetes mellitus were examined. In all patients, the clinical manifestations of heart failure, asthenia, anxiety, depression, the concentration of glucose, glycated hemoglobin, iron, ferritin, transferrin, soluble transferrin receptors, hepcidin, erythropoietin, NT-proBNP were studied, echocardiography was performed in one-dimensional, two-dimensional and Doppler modes (wave, constant-wave and tissue) in standard positions according to the generally accepted technique. Iron deficiency was diagnosed in 42 patients. We have established that the deficiency of iron stores in patients with heart failure and diabetes mellitus contributes to an increase in the clinical manifestations of heart failure, asthenia, anxiety and worsens the indicators of central hemodynamics.It was found that the deficiency of iron store in patients with heart failure and diabetes mellitus contributes to the disruption of various links of iron metabolism and an increase in the clinical manifestations of heart failure, asthenia, anxiety and deterioration of central hemodynamic parameters.