Iron deficiency anemia in patients receiving home total parenteral nutrition

Khaodhiar, Lalita; Keane-Ellison, Mary; Tawa, Nicholas E.; Thibault, Ann; Burke, Patricia A.; Bistrian, Bruce R.

doi:10.1177/0148607102026002114

Cited by 37 publications

(32 citation statements)

References 20 publications

(25 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Acute beriberi with severe thiamine deficiency has been reported and can be life threatening [61]. Iron deficiency anemia is common with TPN [62], and clinically significant sequelae can be seen with deficiencies of selenium [63], copper [64], zinc [65], and chromium [66]. Conversely, trace element toxicity can have serious effects, as with manganese neurotoxicity, which may develop with concomitant cholestatic liver disease [67], and aluminum-related bone disease, as described previously.…”

Section: Other Metabolic Disordersmentioning

confidence: 90%

Metabolic and catheter complications of parenteral nutrition

Ghabril

Aranda-Michel

Scolapio

2004

Curr Gastroenterol Rep

View full text Add to dashboard Cite

Since its introduction in the 1960s, total parenteral nutrition (TPN) has played a vital role in improving clinical outcomes for patients with acute and chronic illnesses. The evolution of TPN solutions and vascular access techniques, combined with an increased awareness and better understanding of the physiology of TPN, have improved the safety of this therapy. Nevertheless, complications are not uncommon and can be life threatening. This article provides an updated review on the metabolic and catheter complications associated with TPN.

show abstract

Section: Other Metabolic Disordersmentioning

confidence: 90%

Metabolic and catheter complications of parenteral nutrition

Ghabril

Aranda-Michel

Scolapio

2004

Curr Gastroenterol Rep

View full text Add to dashboard Cite

show abstract

“…Iron deficiency is common in HPN patients [72], but iron is not routinely available in North America in PN formulations for several reasons, including concerns with stability in fat emulsion [5]. It is available for the addition in PN in other markets.…”

Section: Trace Elementsmentioning

confidence: 99%

Trace Elements in Parenteral Nutrition: Considerations for the Prescribing Clinician

2017

View full text Add to dashboard Cite

Trace elements (TEs) are an essential component of parenteral nutrition (PN). Over the last few decades, there has been increased experience with PN, and with this knowledge more information about the management of trace elements has become available. There is increasing awareness of the effects of deficiencies and toxicities of certain trace elements. Despite this heightened awareness, much is still unknown in terms of trace element monitoring, the accuracy of different assays, and current TE contamination of solutions. The supplementation of TEs is a complex and important part of the PN prescription. Understanding the role of different disease states and the need for reduced or increased doses is essential. Given the heterogeneity of the PN patients, supplementation should be individualized.

show abstract

“…IDA is a common complication associated with long‐term HPN 74 . In HPN patients with no enteral or parenteral iron source, the rate of IDA has been reported in 31%–54% of adults 75 . The length of time to developing IDA is highly variable and can range from 2 to 149 months after initiation of HPN 74 …”

Section: Long‐term Metabolic Complicationsmentioning

confidence: 99%

Metabolic Complications of Home Parenteral Nutrition

Davila

Konrad

2017

Nut in Clin Prac

View full text Add to dashboard Cite

Home parenteral nutrition (HPN) has benefited countless patients since its initiation almost 5 decades ago. Over time, HPN has been found to be associated with various complications, including metabolic disorders. Metabolic complications can be grouped into short-term (eg, fluid imbalance, electrolyte disturbances, glucose abnormalities) and long-term (eg, hepatobiliary disorders, metabolic bone disease, iron deficiency anemia, manganese toxicity) categories. There are a number of treatment options for each complication. It is important to evaluate the entire clinical picture prior to initiating an intervention and use evidence-based interventions when available. A dedicated multidisciplinary team is best suited to prevent and manage complications when they are identified.

show abstract

Iron deficiency anemia in patients receiving home total parenteral nutrition

Abstract: Iron-deficiency anemia is common in patients receiving chronic HPN. Regular small doses of iron in HPN formula, rather than total dose infusion, is the preferred treatment.

Cited by 37 publications

References 20 publications

Metabolic and catheter complications of parenteral nutrition

Metabolic and catheter complications of parenteral nutrition

Trace Elements in Parenteral Nutrition: Considerations for the Prescribing Clinician

Metabolic Complications of Home Parenteral Nutrition

Contact Info

Product

Resources

About