Iron Deficiency Anemia in Children with Congenital Heart Disease and the Usefulness of Erythrocyte Indexes as a Screening Tool.

Binh, Truong Quang; Suong, Nguyen Thi Bang; Định, Nguyễn Hoàng; Anh, Vo Tuan; Thanh, Vu Tri; Khoi, Le Minh

doi:10.4066/2591-7951.1000049

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…No difference was observed between study groups in terms of age and gender (p>0.05). Binh TQ et al, 18 in their study observed majority of cases between 1-5 years with mean age of 2.9 years. Equal gender distribution was noted in the study.…”

Section: Demographymentioning

confidence: 83%

Prevalence of iron deficiency anaemia in congenital heart disease in children

Vineela,

Bhagyawant,

Venkatramani

2023

IPCB

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Background: Congenital heart disease (CHD), out of all congenital anomalies, is the leading condition of mortality and morbidity in children under 5 years of age. Iron deficiency anaemia (IDA) has been clearly shown to be an important risk factor that increases morbidity and mortality in such patients. The present study is thus conducted to find out the prevalence of iron deficiency anaemia in children less than 15 years with congenital heart disease at a tertiary care centre and compare them with cases without CHD. Methods: Prospective study over a period of 2 years, included 60 cases of children below 15 years of age with echocardiographicaly confirmed CHD, investigated by serum ferritin to diagnosed IDA using cut off 12ng/ml. These cases compared with similar age controls. Results: 51cases (82%) were of acyanotic heart disease and 18% were of cyanotic heart disease. Iron deficiency or storage depletion was seen in 90% cases as compared to 75% controls. Iron deficiency anaemia was seen in 55% cases as compared to 30% controls, the difference was statistically significant. Conclusions: Present study observed higher prevalence of IDA among cases with CHD as compared to general population of children. The prevalence was found to be more in cases with cyanotic heart disease as compared to cases with acyanotic heart disease. We thus conclude that routine screening for iron deficiency should be done for these children and those found to be deficient should be treated.

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Section: Demographymentioning

confidence: 83%

Prevalence of iron deficiency anaemia in congenital heart disease in children

Vineela,

Bhagyawant,

Venkatramani

2023

IPCB

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“…This may result in an increased erythrocyte count and elevated blood viscosity, which contributes to the depletion of iron stores [ 7 ]. Even though polycythemia is associated with children who have cyanotic CHD, mostly both acyanotic and cyanotic children have the same high risk of having iron store depletion and iron deficiency anemia [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Anemia in Children with Congenital Heart Disease: A Finding from Low-Resource Setting Hospitals

Kumsa,

Woldesenbet,

Mulugeta

et al. 2024

International Journal of Pediatrics

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Introduction. Congenital heart disease (CHD) is the most common birth defect. Anemia is the prevailing manifestation of micronutrient deficiency. It has been demonstrated that anemia in children increases morbidity and has a negative impact on psychomotor development. Despite its negative consequences, which have been documented for a long time in clinical practice, the issue does not gain sufficient attention in developing countries, specifically in children with CHD. Thus, this study is aimes to assess the prevalence of anemia and the factors associated in children with CHD. Methods. Institutional-based cross-sectional study was conducted on CHD children at selected governmental hospitals in Addis Ababa, Ethiopia, from February to March 2021. During this period, 373 children with acyanotic and cyanotic heart disease between 0 months and 15 years of age were included in this study. All children were assessed using structured questionnaires and anthropometric measurements. Recent hemoglobin results that are avaliable in the medical charts of children were used to diagnose anemia. The data were analyzed using SPSS version 25. Results. From randomly included 373 children with CHD, 298 (79.9%) had acyanotic congenital heart disease (ACHD) and 75 (20.1%) had cyanotic congenital heart disease (CCHD). Twenty-five (33.3%) CCHD and 192 (64.4%) ACHD cases of children were malnourished. The most common type of CCHD and ACHD defects were ventricular septal defects and tetralogy of fallout, respectively. Overall, the prevalence of anemia in ACHD and CCHD was 24.5% and 72%, respectively. In children with ACHD, the frequency of anemia was reported to be significantly higher in the malnourished group than in the well-nourished. Conclusions. A high prevalence of anemia is observed in children with CHD. This study highly suggests further evaluation to determine the frequency and complications of blood indices and other hematological impairments in ACHD, CCHD, and children with both problems. Moreover, the findings of this study on illness profiles in children with CHD prompt further research into the cellular and molecular mechanisms underlying immune system dysfunction.

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Management of Hematologic Abnormalities in Patients with Cyanotic CHD

Bin Jamil,

Ismail

2024

Manual of Pediatric Cardiac Care

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Iron Deficiency Anemia in Children with Congenital Heart Disease and the Usefulness of Erythrocyte Indexes as a Screening Tool.

Cited by 3 publications

References 8 publications

Prevalence of iron deficiency anaemia in congenital heart disease in children

Prevalence of iron deficiency anaemia in congenital heart disease in children

Anemia in Children with Congenital Heart Disease: A Finding from Low-Resource Setting Hospitals

Management of Hematologic Abnormalities in Patients with Cyanotic CHD

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