Iron deficiency anemia

Swain, Randall A.; Kaplan, Barbara; Montgomery, Emily

doi:10.3810/pgm.1996.11.116

Cited by 15 publications

(4 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The simultaneous use of dairy products, egg yolks, coffee, tea, antacids, or fiber reduces the absorption of oral iron. Parenteral administration of iron is recommended in patients with oral iron intolerance, inadequate absorption, chronic or severe blood loss, or nonresponsiveness to treatment [ 19 ] .…”

Section: Resultsmentioning

confidence: 99%

Therapeutic Options to Minimize Allogeneic Blood Transfusions and Their Adverse Effects in Cardiac Surgery: A Systematic Review

Santos¹,

Silva²,

Silva³

et al. 2014

Revista Brasileira De Cirurgia Cardiovascular

View full text Add to dashboard Cite

IntrodutionAllogeneic blood is an exhaustible therapeutic resource. New evidence indicates that blood consumption is excessive and that donations have decreased, resulting in reduced blood supplies worldwide. Blood transfusions are associated with increased morbidity and mortality, as well as higher hospital costs. This makes it necessary to seek out new treatment options. Such options exist but are still virtually unknown and are rarely utilized.ObjectiveTo gather and describe in a systematic, objective, and practical way all clinical and surgical strategies as effective therapeutic options to minimize or avoid allogeneic blood transfusions and their adverse effects in surgical cardiac patients.MethodsA bibliographic search was conducted using the MeSH term “Blood Transfusion” and the terms “Cardiac Surgery” and “Blood Management.” Studies with titles not directly related to this research or that did not contain information related to it in their abstracts as well as older studies reporting on the same strategies were not included.ResultsTreating anemia and thrombocytopenia, suspending anticoagulants and antiplatelet agents, reducing routine phlebotomies, utilizing less traumatic surgical techniques with moderate hypothermia and hypotension, meticulous hemostasis, use of topical and systemic hemostatic agents, acute normovolemic hemodilution, cell salvage, anemia tolerance (supplementary oxygen and normothermia), as well as various other therapeutic options have proved to be effective strategies for reducing allogeneic blood transfusions.ConclusionThere are a number of clinical and surgical strategies that can be used to optimize erythrocyte mass and coagulation status, minimize blood loss, and improve anemia tolerance. In order to decrease the consumption of blood components, diminish morbidity and mortality, and reduce hospital costs, these treatment strategies should be incorporated into medical practice worldwide.

show abstract

Section: Resultsmentioning

confidence: 99%

Therapeutic Options to Minimize Allogeneic Blood Transfusions and Their Adverse Effects in Cardiac Surgery: A Systematic Review

Santos¹,

Silva²,

Silva³

et al. 2014

Revista Brasileira De Cirurgia Cardiovascular

View full text Add to dashboard Cite

show abstract

“…Parenteral iron therapy is a readily available method of treatment in patients in whom oral iron therapy is unsuccessful. Parenteral therapy first became available in 1952 (8) and TDI was first used in 1963. However, there have been concerns regarding the safety of TDI.…”

Section: Discussionmentioning

confidence: 99%

Safety and efficacy of total dose infusion of iron dextran in iron deficiency anaemia

Reddy

Kathula

Bekal

et al. 2007

International Journal of Clinical Practice

View full text Add to dashboard Cite

show abstract

“…These products might also be used for the treatment of iron deficiency due to a variety of reasons. Unfortunately, some of the adverse effects restrict their use in children [1,3,4,5,6,7]. Intravenous iron is commonly and safely used in dialysis patients [3, 4].…”

Section: Introductionmentioning

confidence: 99%

Treatment of Iron Deficiency Anemia with Intravenous Iron Preparations

Akarsu

Taşkın²,

Yı́lmaz³

et al. 2006

Acta Haematol

View full text Add to dashboard Cite

Objective: We aimed to determine the effects of intravenous iron therapy on blood parameters in pediatric patients who do not tolerate oral iron therapy for any reason. Patients and Methods: The patient group consisted of candidates for elective operations requiring blood transfusions in order to raise hemoglobin (Hb) concentrations rapidly and for whom oral iron administration is useless and compliance with long-term treatment is definitely impossible due to sociocultural factors. Sixty-two children were included in the study. Venous blood samples were taken at diagnosis, and after 1 week and 1, 2 and 3 months. Hb, hematocrit, erythrocyte indices (mean erythrocyte volume, mean erythrocyte Hb and mean erythrocyte Hb concentration), serum iron (SI) levels, iron binding capacity, transferrin receptor (CD71) and serum ferritin levels were measured. Iron sucrose was used as an intravenous iron preparation. Results: All children showed improvements in iron deficiency anemia. A statistically significant elevation occurred between the time of diagnosis and week 1 (p<0.05) in nearly all parameters. SI was raised until at least 1 month of therapy. There was no significant difference between transferrin receptors measured before and after the intravenous iron therapy. Ferritin did not exceed the values achieved in the 1st month. Mild side effects were encountered in only 8 (12.9%) patients. Treatment was not discontinued because of side effects in any case. The patients in the control group were given an oral form containing ferroglycine sulfate. Conclusion: Intravenous iron therapy can replace oral therapy in patients whose blood parameters must be raised rapidly and in situations where oral iron administration would not be appropriate for any reason. However, reinforcement with oral iron therapy or additional intravenous doses would be appropriate.

show abstract

Iron deficiency anemia

Cited by 15 publications

References 12 publications

Therapeutic Options to Minimize Allogeneic Blood Transfusions and Their Adverse Effects in Cardiac Surgery: A Systematic Review

Therapeutic Options to Minimize Allogeneic Blood Transfusions and Their Adverse Effects in Cardiac Surgery: A Systematic Review

Safety and efficacy of total dose infusion of iron dextran in iron deficiency anaemia

Treatment of Iron Deficiency Anemia with Intravenous Iron Preparations

Contact Info

Product

Resources

About