Iron‐Catalyzed Cross‐Dehydrogenative Coupling

Abstract

The sustainable construction of carbon–carbon bonds or carbon–heteroatom bonds is critical for future green chemical synthesis. Cross‐dehydrogenative coupling (CDC) reactions have thus been widely developed as one of the most sustainable and efficient synthetic strategies for such a philosophy. A number of obvious merits of iron catalysts make this reaction model more potential for industrial production and manufacturing applications. Iron‐catalyzed CDC reactions have emerged as a greener strategy for the direct formation of CC and C–heteroatom bonds from easily available compounds. The use of simple, low toxicity, and cheap iron‐based catalysts meets the criteria for the basis of chemical synthesis compared to those high price, toxic, and precious metal catalysts. In this article, we present the development of iron‐catalyzed CDC reactions by some selected results.