Iron-catalyzed carbonylative Suzuki reactions under atmospheric pressure of carbon monoxide

Abstract

The first highly effective iron-catalyzed carbonylative Suzuki reaction has been developed. Substrates with electron-donating or electron-withdrawing functionality, ortho-substitution, as well as active groups proceeded smoothly, affording desired products in high yields. This protocol is economical, environmentally benign and practical for the synthesis of biaryl ketones.

Carbonylative Suzuki‐Miyaura Cross‐Coupling Over Pd NPs/Rice‐Husk Carbon‐Silica Solid Catalyst: Effect Of 1,4‐Dioxane Solvent

“…These results are emphasizing the decisive nature of solvents and catalytic efficiency. According to the literature reports the formation of biaryl ketones and biphenyls in CSMC is quite common . The CSMC investigated with the aim of producing biaryl ketone selectively.…”

“…According to the literature reports the formation of biaryl ketones and biphenyls in CSMC is quite common. [25][26][27][28][29][30][31][32] The CSMC investigated with the aim of producing biaryl ketone selectively. However, the major limitation of CSMC approach often lies in the formation of significant amounts of biphenyl, which results from direct coupling without carbon monoxide insertion.…”

Carbonylative Suzuki coupling reactions catalyzed by ONO pincer–type Pd(II) complexes using chloroform as a carbon monoxide surrogate

“…A summary of the crystallographic and refinement data of complexes is furnished in Table 1 with selected bond lengths and bond angles given in Table S2. (11), 79.92(11)-80.09(9), 85.38(7)-94.09 (5), and 92.16(6)-100.30 (7), respectively. The Pd-O, Pd-N, and Pd-P bond lengths in all complexes are in the range of 1.926(6)-1.993(2) Å, 1.968(5)-1.975(3) Å, and 2.2837(9)-2.2965 (7) Å, respectively, which are in the normal range and similar to other structurally characterized analogous palladium(II) complexes.…”

“…[1] Development of efficient methods for the C-C bond formation is one of the enduring research theme in organic chemistry. [2][3][4] Transition metal-catalyzed carbonylative Suzuki cross-coupling reaction is one of the powerful methods to generate C-C bonds which are an integral part of structural skeleton of a wide variety of natural products, pharmaceutical drugs, agrochemicals, fine chemicals, and organic functional materials [5][6][7][8][9][10] (Figure 1).…”

Dppf‐Ligated Palladium Complex as an Efficient Catalyst for the Synthesis of Biaryl Ketones Using Co2(CO)8 as a C1 Source with High TON and TOF

“…[14] After that a number of modifications on the synthesis of biaryl ketones have been developed. Most of the reports involves a variety of homogeneous and heterogeneous palladium catalysts, [15][16][17][18][19][20][21][22][23][24][25][26][27] Nevertheless, these existing methods…”