Iron-caseinglycomacropeptide complexes: Characterization and application in beverages

Morales, Ramón; Martínez, María Julia; Pilosof, Ana M.R.

doi:10.1016/j.foodres.2020.109772

Cited by 6 publications

(3 citation statements)

References 54 publications

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“…When metal ions complex with amino acid residues of peptides, significant changes in the shifts of the absorption peaks could be observed in the FTIR spectra . Compared with the signal of OPH, the characteristic wavenumber of the OPH–Fe complex shifted from 3348 to 3340 cm –1 (Figure E), indicating that the amino group might be involved in the chelation and a change in the vibration frequency of the N–H bond occurred .…”

Section: Resultsmentioning

confidence: 97%

“…23 When metal ions complex with amino acid residues of peptides, significant changes in the shifts of the absorption peaks could be observed in the FTIR spectra. 24 Compared with the signal of OPH, the characteristic wavenumber of the OPH−Fe complex shifted from 3348 to 3340 cm −1 (Figure 2E), indicating that the amino group might be involved in the chelation and a change in the vibration frequency of the N−H bond occurred. 6 Similarly, the changes in the characteristic peak of the carboxyl group after the addition of iron (from 1516 to 1518 cm −1 ) indicated that the iron-chelating site of OPH was also related to the carboxyl group on the peptide chain.…”

Section: Characterization Of Conformational Properties Of Oph and The...mentioning

confidence: 96%

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Characterization of Oyster Protein Hydrolysate–Iron Complexes and their In Vivo Protective Effects against Iron Deficiency-Induced Symptoms in Mice

Liu,

Yu,

Dou

et al. 2023

J. Agric. Food Chem.

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Iron is one of the trace mineral elements, and iron deficiency is a common phenomenon that negatively influences human health. Food-derived iron supplements were considered excellent candidates for improving this syndrome. In this work, oyster-protein hydrolysates (OPH) and ferrous chloride successfully formed the OPH−Fe complex (6 mg/mL, 40 °C, 30 min), where the main binding sites involved were the carboxyl and amino groups. The OPH−Fe complex showed no obvious changes in the secondary structure, while the iron changed the morphological appearance and also showed fluorescence quenching, an ultraviolet shift, and an increase in size distribution. The OPH−Fe complex showed better dynamic absorption of iron (64.11 μmol/ L) than ferrous sulfate (46.90 μmol/L), and the medium dose had better protective effects against iron-deficiency anemia in vivo. Three representative peptides (DGKGKIPEE, FAGDDAPRA, and VLDSGDGVTH) that were absorbed intact were identified. This experiment provided a theoretical foundation for further study of the digestion and absorption of the OPH−Fe complex.

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Section: Resultsmentioning

confidence: 97%

Section: Characterization Of Conformational Properties Of Oph and The...mentioning

confidence: 96%

Characterization of Oyster Protein Hydrolysate–Iron Complexes and their In Vivo Protective Effects against Iron Deficiency-Induced Symptoms in Mice

Liu,

Yu,

Dou

et al. 2023

J. Agric. Food Chem.

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“…Fourier transform infrared spectrometry was performed as described previously ( 34 ). In total, 1 mg of freeze-dried CCP and CCP–Zn were mixed with 100 mg of dry KBr.…”

Section: Methodsmentioning

confidence: 99%

Chicken skin-derived collagen peptides chelated zinc promotes zinc absorption and represses tumor growth and invasion in vivo by suppressing autophagy

Liu

Zou²,

Ji³

et al. 2022

Front. Nutr.

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To improve the utilization value of chicken by-products, we utilized the method of step-by-step hydrolysis with bromelain and flavourzyme to prepare low molecular weight chicken skin collagen peptides (CCP) (<5 kDa) and characterized the amino acids composition of the CCP. Then, we prepared novel CCP-chelated zinc (CCP–Zn) by chelating the CCP with ZnSO4. We found that the bioavailability of CCP–Zn is higher than ZnSO4. Besides, CCP, ZnSO4, or CCP–Zn effectively repressed the tumor growth, invasion, and migration in a Drosophila malignant tumor model. Moreover, the anti-tumor activity of CCP–Zn is higher than CCP or ZnSO4. Furthermore, the functional mechanism studies indicated that CCP, ZnSO4, or CCP–Zn inhibits tumor progression by reducing the autonomous and non-autonomous autophagy in tumor cells and the microenvironment. Therefore, this research provides in vivo evidence for utilizing chicken skin in the development of zinc supplements and cancer treatment in the future.

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A comparation between different iron sources on growth performance, iron utilization, antioxidant capacity and non-specific immunity in Eriocheir sinensis

Song

Wang

et al. 2022

Animal Feed Science and Technology

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Iron-caseinglycomacropeptide complexes: Characterization and application in beverages

Cited by 6 publications

References 54 publications

Characterization of Oyster Protein Hydrolysate–Iron Complexes and their In Vivo Protective Effects against Iron Deficiency-Induced Symptoms in Mice

Characterization of Oyster Protein Hydrolysate–Iron Complexes and their In Vivo Protective Effects against Iron Deficiency-Induced Symptoms in Mice

Chicken skin-derived collagen peptides chelated zinc promotes zinc absorption and represses tumor growth and invasion in vivo by suppressing autophagy

A comparation between different iron sources on growth performance, iron utilization, antioxidant capacity and non-specific immunity in Eriocheir sinensis

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