Iron bioavailability from ferric pyrophosphate in rats fed with fructan-containing yacon (Smallanthus sonchifolius) flour

Abstract

a b s t r a c tThe effects of inulin-type fructans (ITF)-containing yacon flour (YF) on Fe bioavailability from ferric pyrophosphate (FP) were evaluated in Fe-deficient rats using the Hb repletion efficiency (HRE) assay. Weanling male Wistar rats were fed a low-Fe diet (12 mg/kg) for 15 days followed by 2 weeks of Fe repletion with diets providing 35 mg Fe/kg as either ferrous sulphate (FS) or FP, supplemented with 7.5% ITF as either YF or Raftilose (RAF), a purified ITF. ITF increased caecal fermentation, whereas YF was more butyrogenic than RAF. ITF improved HRE in FP-fed rats, and those fed YF had a higher relative biological value compared with those fed FP and RAF. Liver Fe was increased by ITF, but only YF led to values similar to those in the FS group. It is observed that ITF increased caecal fermentation and Fe bioavailability. These effects were more pronounced when YF was the ITF source.

Evaluation of iron bioavailability in a mixture of cereals, seeds, and grains ("Human Ration")

“…Weber et al (2010) found significant reduction in the intestinal pH in animals fed a diet containing a mixture with high fiber content. Other authors found similar results, especially in diets supplemented with soluble dietary fiber (Scholz-Ahrens & Schrezenmeir, 2002;Lobo et al, 2011).…”

“…However, other studies have pointed out that anemic animals fed soluble fiber showed recovery of hemoglobin similar to that of the control group; in those studies, ferrous sulfate was used as the control diet (De Cássia Freitas et al, 2006;Feltrin et al, 2009). The lack of consensus among various studies is due to experimental conditions such as short-term or long-term consumption of the food test, experimental models, the food matrix, and the age and/or nutritional/physiologic status of the animals (Lobo et al, 2007(Lobo et al, , 2011Scholz-Ahrens & Schrezenmeir, 2007).…”

“…Fermentation of this fiber in the large intestine results in the production of short chain fatty acids (SCFA) that are used as energy source by colonocytes, as well as the reduction of luminal pH which may enhance minerals solubility and absorption (Scholz-Ahrens & Schrezenmeir, 2007;Lobo et al, 2011).…”

Yacon: benefícios à saúde e aplicações tecnológicas

“…Também atuam melhorando a regularização da função intestinal, através da eliminação de bactérias patogênicas e putrefativas por efeito da multiplicação das bifidobactérias (GIBSON & ROBERFROID, 1995;AYBAR et al, 2001;GUIGOZ et al, 2002;PEREIRA & GIBSON, 2002;COUNDRAY et al, 2003;ALBUQUERQUE & ROLIM, 2011;LOBO et al, 2011;DE MOURA et al, 2012).…”

Dietary Iron Overload: Short- and Long-Term Effects on Cecal Morphometry in Growing Rats

“…The cecum and its contents were removed, weighed, placed in a Petri dish with ice (16) and cut open along the small curvature. The cecal content pH was measured in situ by inserting an electrode (UP-25; Denver Instrument, Denver, CO) through the ileocecal junction, as described previously (17). Cecal tissue samples were collected and fixed in 10% formaldehyde solution, stored in 70% ethanol and further used for histological and morphometric analyses.…”